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Biomedical subjects

D A Miller

Publications and source records attributed to D A Miller.

At least 253 records · Page 14Linked to original sources
PubMed1973

Chromosome markers in Mus musculus: strain differences in C-banding.

The mitotic chromosomes of several inbred strains of mice and a series of F(1) hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F(1) hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.

Animals↗
PubMed1972

Chromosome mapping in the mouse, fluorescence banding techniques permit assignment of most genetic linkage groups.

Chromosome banding techniques have permitted the identification of every normal chromosome in the mouse, Mus musculus, and the demonstration of strain differences. By identifying the chromosomes involved in a series of translocations, it has been possible to assign 14 of the 19 known linkage groups to 14 different chromosomes. These powerful cytological methods promise to revolutionize cytogenetic studies in higher organisms.

Animals↗
PubMed1971

In vitro techniques for avoiding edge damage in studies of frog skin.

Frog skins mounted between chambers without compression, with a liquid insulator and a tissue adhesive, were studied in vitro. Since voltage and electrical resistance per unit area were unchanged by a tenfold decrease in area of skin studied, it is concluded that these mounting techniques do not produce edge damage and consequently provide a means for study of the skin in its absence.

Acrylates↗