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Biomedical subjects

D A James

Publications and source records attributed to D A James.

30 records · Page 2Linked to original sources

Cells of the adenohypophysis of the mink (Mustela vison) identified by immunohistochemical and functional criteria.

Six cell types were described in the adenohypophysis of the mink, and a putative function was assigned to each type. These cells are the two types of gonadotrophic cells, a thyrotrophic hormone (TSH) cell, a somatotrophic (STH) cell, a prolactin (PRL) cell and a corticotrophin-producing (ACTH) cell. Gonadotrophic cells were identified by an immunolocalization technique using antisera to ovine LH. TSH cells and ACTH cells were identified by ablation of respective target organs and observation of the subsequent hypertrophic cells in the pituitary, as well as comparison with published descriptions in other species. STH cells were identified by comparison with published reports. PRL cells were observed in lactating animals and animals in lactational withdrawal.

Adrenocorticotropic Hormone↗

Diagnosis and management of hypothyroidism in pregnancy.

Hypothyroidism is not a common occurrence in pregnancy, but it is important that nurse practitioners recognize it early. Complications of hypothyroidism in pregnancy are pregnancy-induced hypertension, preeclampsia, abruptio placentae, low birth weight and stillbirth, and fetal distress in labor. Careful monitoring of pregnant women for hypothyroidism and correction with levothyroxine therapy can prevent these complications. During pregnancy, the thyroxine needs of women with hypothyroidism are increased, and their dosage of levothyroxine should be individualized. Nurse practitioners can provide holistic care to the woman with hypothyroidism to ensure optimal maternal and fetal health.

Female↗