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Biomedical subjects

D A Hansen

Publications and source records attributed to D A Hansen.

7 recordsLinked to original sources
PubMed1979

Effect of alprenolol on mortality among patients with definite or suspected acute myocardial infarction. Preliminary results.

A double-blind study of alprenolol versus placebo was done in patients with definite or suspected myocardial infarction to show the effect of the drug on mortality-rate after a year of treatment in patients aged less than or equal to 65 and to study the tolerance of the drug by patients greater than 65 years of age. The dose given was 5--10 mg intravenously, followed by 200 mg twice a day, orally. Patients in whom beta-blockade was contraindicated were excluded. All deaths, side-effects, and dropouts were recorded. Of the 480 patients in the study, 238 patients received alprenolol and 242 placebo. During the year of follow-up 108 patients dropped out from the study. Mortality was not reduced in patients greater than 65 years of age. In those less than or equal to 65 years alprenolol significantly reduced mortality-rate (20% mortality in placebo group vs 9% in treated group). There was also a significant reduction in mortality-rate among those with definite infarction (28% in the placebo vs 15% in the treated group).

Acute Disease↗
PubMed1978

Angiofollicular lymph node hyperplasia.

One case of angiofollicular lymph node hyperplasia simulating a salivary gland tumour is presented. In a review of the literature containing some 220 cases, 29 cases in the neck were found. A survey of these 29 cases is given, and another two cases of special oto-rhino-laryngologic interest are mentioned. Furthermore, a description of the tumour and a brief discussion of aetiology and differential diagnosis are given.

Diagnosis, Differential↗
PubMed1978

beta-Cyclodextrin as an aid to peritoneal dialysis. Renal toxicity of beta-cyclodextrin in the rat.

A peritoneal dialysate containing beta-cyclodextrin has been shown to accelerate the removal of intravenously administered phenobarbital in rats. It was found that high concentrations of beta-cyclodextrin were toxic to the animals in the single exchange technique employed. The renal toxicity was estimated by measuring blood urea nitrogen values in the rats following oral and intraperitoneal administration of the cyclic amylose.

Amylose↗