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Biomedical subjects

D A CAHAL

Publications and source records attributed to D A CAHAL.

16 recordsLinked to original sources
PubMed1965

CARDIAC PACEMAKERS.

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Cardiovascular Diseases↗
PubMed1958

Analgesic activity of (+)-1-(3-methyl-4-morpholino-2:2-diphenylbutyryl) pyrrolidine (R.875) in student volunteers.

(+)-1-(3-Methyl-4-morpholino-2:2-diphenylbutyryl)pyrrolidine (R.875) raised the threshold to ischaemic pain in healthy human volunteers. The peak effect for all doses was reached after about 2 hr. The drug frequently caused nausea and vomiting but no euphoria. Muscular weakness was experienced by many subjects and was sometimes followed 1 to 2 hr. later by hiccup and muscle twitching, suggesting that R.875 may have an effect on striped muscle.

Analgesics↗
PubMed1957

Analgesic activity of dipipanone hydrochloride in student volunteers.

Dipipanone hydrochloride raised the threshold to ischaemic pain in healthy human volunteers. The lowest dose producing a significant rise in pain threshold was 10.0 mg. The peak effect for all doses was reached after about 2 hr. Side effects, the most common of which were drowsiness, nausea, and vertigo, are described and analysed. The drug was shown to be a histamine liberator and to cause pain and tenderness at injection sites.

Analgesics↗