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Biomedical subjects

D A Buser

Publications and source records attributed to D A Buser.

6 recordsLinked to original sources
PubMed1998

Implants in regenerated bone: long-term survival.

This retrospective multicenter study analyzed 526 implants placed and loaded in regenerated bone. Both autogenous and allogeneic bone grafts were used in combination with a barrier membrane to reconstruct bone using either a simultaneous or staged approach. Implants were followed from 6 to more than 74 months postloading. Eight of the implants were lost, for a success rate of 97.5%. The type of graft material did not affect the clinical success of the implants, nor did the use of submerged versus nonsubmerged implants or a staged versus a simultaneous approach. In conclusion, regenerated bone reacted to implant placement in a manner that was clinically similar to native bone.

Adolescent↗
PubMed1997

Clinical trials on implants in regenerated bone.

The lack of a sufficient volume of healthy jaw bone was the most important local contraindication for the placement of dental implants in the 1980s. Thus, several attempts have been made in the past 10 years to develop new surgical methods for the reconstruction of lost jaw bone in potential implant patients. At present, methods such as guided bone regeneration utilizing barrier membranes or sinus lift procedures are widely used in dental offices. There are, however, some concerns about the efficacy and predictability of these procedures. There is a need to determine how new bone regenerative procedures should be properly evaluated. The goal of the present paper is to establish some guidelines for clinical trials on implants in regenerated bone. It is proposed that such trials should be conducted in two main phases according to predetermined endpoints. The first main phase evaluates the new bone regenerative procedure. This almost always requires an initial development period including step-by-step modifications to identify essential surgical factors for the achievement of successful treatment outcomes. At the end, the surgical protocol will be established in detail. This is followed by the validation period to evaluate efficacy and predictability of this surgical protocol in a clinical study with consecutively treated patients. After successful bone regeneration has been properly documented, the second main phase evaluates the implants inserted in regenerated bone in a prospective clinical study utilizing the same protocol as for implants in pristine, non-regenerated bone. This documentation allows the evaluation of tissue integration of these implants and their 5-year success rates.

Alveolar Ridge Augmentation↗
PubMed1997

Hard-tissue augmentation for the placement of anterior dental implants.

Dental implants have become a popular alternative for replacing missing teeth in every region of the oral cavity. In the anterior zone, special esthetic concerns require not only a stably anchored implant for long-term success, but also the presence of adequate hard and soft peri-implant tissues. Anterior tooth loss is often accompanied by considerable loss of alveolar bone, so augmenting hard tissue before or in combination with implant placement becomes a critical part of therapy. One of the most successful augmentation techniques is guided bone regeneration (GBR). Thus far, augmentation procedures using expanded polytetrafluoroethylene membranes (ePTFEa) have proved to be the most efficient and predictable surgical technique to enhance deficient bone sites. This article discusses some critical biological and clinical/technical aspects of GBR and describes techniques for anterior hard-tissue augmentation with the photographic documentations of three clinical cases.

Alveolar Bone Loss↗
PubMed1989

ITI-system. Basic and clinical procedures.

Future development in implant prosthodontics should be based on the fundamentals of sound research and reliable clinical implementation. The goals should be to research the safety and efficacy of implants with regard to materials, host receptor site and interfacial zone; to develop acceptable uniform standards of evaluation; and to submit findings to scientific methods of analysis in determining benefit-to-risk factors. This presentation will offer a glimpse at some current developments in basic and clinical research focusing on studies in biocompatibility and host acceptance; the implant-tissue interface; processes in osteogenesis related to vascularization of host sites; and bioengineering studies related to stress analysis and dimensional accuracy of impression systems for implants. The presentation will further describe future directions in research, training and implementation of services through development of an interdisciplinary team. A center is proposed to address the need for combined efforts in clinical++ and basic science research, the broad scope of implant utilization, and the teaching of implant procedures within an academic setting and to our colleagues.

Biocompatible Materials↗