Biomedical subjects
Publications and source records attributed to D A Booth.
Injection of 6 micrograms of aqueous norepinephrine elicits eating only when it takes place at sites within a limited region of the rat brain. The distribution of effective sites coincides with that of systems connected to an extrahypothalamic pathway between the limbic forebrain and tegmental motor systems. It does not correspond to those parts of the lateral hypothalamus thought to control normal feeding.
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The molar ratios of N-acetyl neuraminic acid, hexose, hexosamine, and sphingosine have been determined for the abnormal ganglioside in Tay-Sachs disease that was previously detected as a fast-moving band in thin-layer chromatography, and in two abnormal fast-moving bands of gangliosides from the cortex and white matter of the brain in cases of gargoylism and Niemann-Pick's disease. The fastest-moving ganglioside band in these two conditions contains neither hexosamine nor glucose.
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