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Biomedical subjects

D A Boon

Publications and source records attributed to D A Boon.

9 recordsLinked to original sources

Primary care guidelines from an organizational point of view.

Guidelines in primary health care have been developed to reduce assumed and undesired variation in certain aspects of care delivery by professionals. If systematically applied guidelines no doubt effect the quality of care. It is argued however that taking an organizational point of view on quality management yields new requirements with respect to development and application of guidelines. It is considered to be essential for managerial control purposes that guidelines have simple and valid indicators to monitor the actual application and to measure the preferred outcome. It is essential that the choice of guidelines to be implemented in an organization is determined in the context of an explicit plan for quality management.

Humans↗

Otology in Nepal.

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Adolescent↗

[Big spleen, big problems].

The history of a Moroccan girl is described with splenomegaly, lymphadenopathy and pancytopenia after a holiday in her native country. Bone marrow smears were considered negative for Leishmaniasis in four different laboratories. All other diagnostic options could also not be confirmed. Reexamination of the bone marrow smears in a laboratory for tropical diseases revealed Leishmania donovani organisms. Treatment with sodium antimony gluconate was successful. Epidemiology, symptoms and diagnostic problems are discussed.

Antimony Sodium Gluconate↗

Medical adventure in Nepal.

In 1977 a request for teaching of otologic surgery from a Nepalese doctor to a Canadian colleague resulted in Doctor David Boon and his wife, Joan, travelling to Nepal in February, 1979, as volunteers. They participated in the "Lions Club of Kathmandu First Free Ear Camp" sponsored jointly by the International Sound Foundation Society and the Lions Club of Kathmandu. Fifteen hundred patients were seen and otosclerosis was one of the commonest ear diseases encountered. Adhesive otitis media with attic cholesteatoma was prevalent and a few cases of childhood serous otitis media were diagnosed. Severe sensorineural hearing loss was also prevalent and related to heredity, post febrile illness, and ototoxic drugs. Seventy surgical procedures were performed consisting of mastoidectomy, stapes reconstruction, tympanoplasty and myringotomy.

Humans↗

Testosterone production by XYY subjects.

A study of plasma concentration (P1T, ng/ml), metabolic clearance rate (MCRT, L/day) and blood production rate (PBT, mg/day) was done on seven XYY subjects of various ages and four pair-matched control XY subjects by a radioinfusion technique of 1,2-3H-testosterone. Although MCRT showed no significant difference between the groups, P1T and PBT were significantly lower (P less than 0.05) in XYY subjects. Therefore, increased aggressive behavior of the XYY subjects can not be attributed to increased levels or production rates of testosterone.

Adolescent↗