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Biomedical subjects

Connie Jørgensen

Publications and source records attributed to Connie Jørgensen.

6 recordsLinked to original sources

Acute recurrent polyhydramnios: a combination of amniocenteses and NSAID may be curative rather than palliative.

Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks' gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days' gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.

Acute Disease↗

[Prenatal diagnosed hydronephrosis and other urological anomalies].

By renal ultrasound examination, urological anomalies may be demonstrated in 1-2% of fetuses and in about 0.5% of newborns. Boys have about twice the frequency of girls. Surgical treatment is indicated in about one fourth of these urological anomalies. If all pregnant women in Denmark were to have fetal ultrasound examination of the kidneys and the urinary tract, about 70 children would be born each year with a prenatally diagnosed urological anomaly for which surgical procedure is or will be indicated. This paper provides Danish guidelines for prenatal diagnosis, follow-up and intervention in cases of urological anomalies and guidelines for post-natal diagnosis, follow-up and treatment of these anomalies, especially hydronephrosis.

Abnormalities, Multiple↗

[Fetal therapy].

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Congenital Abnormalities↗

[The possibility of discovering congenital defects before birth by means of prenatal ultrasound screening].

Ultrasound examination during pregnancy is now an essential part of modern obstetrical management. In many European countries women are offered 1-3 ultrasound examinations during their pregnancy. In Denmark a similar offer is available but only to a very limited extent. Ultrasound examinations are performed on medical reasons. Modern equipment, trained sonographers, and the increasing use of ultrasound scannings imply that a considerable number of fetal malformations are diagnosed. A very comprehensive literature is available describing the sensitivity of diagnosing a fetal malformation at different times during the pregnancy. In a number of studies the sensitivity within different organ systems has been given as well. Intrauterine treatment is afield with great development, in which the more invasive operative techniques are replaced by laparoscopic procedures.

Congenital Abnormalities↗