Erectile dysfunction and scleroderma.
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Adrenergic alpha-Antagonists↗
Biomedical subjects
Publications and source records attributed to Catharine Dewar.
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Yohimbine is a selective alpha-2 adrenergic antagonist that has been used in the pharmacologic management of erectile dysfunction (ED). We describe a patient with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) who paradoxically experienced worsening of Raynaud's phenomenon when using yohimbine for ED.