[Localized prostate cancer].
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Brachytherapy↗
Biomedical subjects
Carlos Rodríguez Duarte
Publications and source records attributed to Carlos Rodríguez Duarte.
[Use of brachytherapy in the treatment of localized prostate cancer. Preliminary report].
OBJECTIVE: We emphasize the good results obtained by authors of the United States of North America and Europe using prostate brachytherapy in the treatment of localized prostate cancer. METHODS: We report 50 patients with stage T1c-T2c treated during the last twenty one months (September 2000, June 2001). Two groups were made--according to Gleason, PSA, local infiltration and percentage of tumor volume in the Biopsy--in low and high risk patients. We report the methodology used in the surgical procedure. RESULTS: We found the nadir of PSA was 0.5-1 in seven patients followed during eighteen months, and fifteen patients followed during twelve months. We had a failure in two patients. A reference is made about two patients with previously TURP and one with open prostatectomy, with very good post-operative results. Secondary effects are essentially irritative symptoms, well controlled by medical treatment. Four patients had acute urinary retention, one of them persistent. Normal erections were found in thirty five patients, and partial in fifteen, which had a very good respond to Sildenafil. Four cases had partial incontinence, currently only one persist during sleep. CONCLUSION: We have had very good results during the first twenty one months of treatment of cancer of the prostate with brachytherapy. In our opinion the procedure is a very valid option of treatment for this disease.
Adenocarcinoma↗
[Multi-core prostatic biopsy].
OBJECTIVE: A brief revision of the history of the prostate biopsy is done, and emphasis is made in the importance of seek deeply in the diagnostic of small lesions, PIN and atypical prostate hyperplasia. METHODS: A total of 221 patients, are presented. A description of the two groups of patients is made. group I with 148 patients in which the sextant type was performed, and the group II, in which our technique of 12 cores was done, using separated bottles for each core. The complete technique used is described and we used the "T" and Rank Sum Test for the statistical analysis of the results. RESULTS: We found a global 22.9% positive biopsies in the group I. This grew up as we took out more cores, with 25.9% with more than six cores. The global result in group II was 37.1% of positive biopsies (p = 0.03). There were 25 patients with 12 cores, and the rate of positive was 34.2%. Tumor in one core was found in eight patients and also in two to four cores, in the group of ten cores tumor was found in ten patients. No side effects were reported. DISCUSSION: We review the results, and emphasis was made in the necessity of have multiple cores biopsies of the prostate, studying them separate. CONCLUSION: Multi-core biopsy of the prostate is a very useful procedure in the diagnosis of cancer of the prostate with better specificity results, statistically significative, and without side effects.
Adenocarcinoma↗