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Biomedical subjects

C Zippel

Publications and source records attributed to C Zippel.

At least 19 recordsLinked to original sources

[Rehabilitation in cerebrovascular stroke--experiences and results of a treatment concept based on modern neurophysiology knowledge].

The modern concept of rehabilitation of patients with stroke is based on new neurophysiological investigations about processes of movements, learning and memory. Therefore the rehabilitation is multidimensional. The complete patterns of symptoms must be considered. The training of cognitive functions has the same importance as the treatment of disorders of movements. The effects of this concept are investigated in 295 patients in accordance with self-activities and ability of walking. The results have been compared with 101 patients without consideration of all gnostic defects. The results of the modern rehabilitation concept were better. Patients with aphasia having similar good results but patients with diminished ability to cooperation having unfavourable prognosis of rehabilitation.

Activities of Daily Living

[Cytomegalovirus infections after kidney transplantation and passive immunization].

Cytomegalovirus infection after renal transplantation impairs the survival rate of patient and graft. An incidence of 24 to 92% of CMV infections after renal transplantation is reported, but only 15 to 77% of these patients show clinical symptoms. Contaminated donor organs, blood transfusions and reactivation by immunosuppression are the main causes of this infection. Active immunisation cannot prevent the reactivation of the infection, but also antiviral agents can hardly influence the course of the disease. Passive immunisation showed promising effects in bone-marrow transplantation and is now also tried in renal transplantation. The first results of a randomized study do not allow a final conclusion, but show less clinical symptomatic CMV infections, and statistically significant less herpes simplex infections in the group receiving anti CMV IgG prophylaxis.

Antibodies, Viral

[Segmental chlamydia proctitis].

A case report is given of a 28 year old homosexual suffering from segmental proctitis caused by Chlamydia. The patient had watery diarrhea and fever since 3 weeks. Stool specimen testing was negative in regard to Salmonella, Shigella and worm eggs. Infection with N. gonorrhoea, Herpes simplex virus, Toxoplasma gondi, Yersinia and M. tuberculosis could be excluded. Serological testing yielded results suggestive of an old lues infection successfully treated. On histological examination typical reticulocytary suppurating granuloma were found. Therapy of choice of Chlamydia-proctitis is tetracyclines.

Adult

[Polymorphonuclear infiltration of the placenta in cases with internal fetal monitoring (author's transl)].

The infectious morbidity due to intra-amniotic fetal monitoring was studied morphologically in 100 spontaneous deliveries with intra-amniotic fetal monitoring. The control group consisted of 100 spontaneous deliveries with external fetal monitoring. It was shown that internal fetal monitoring does not increase the infectious morbidity with total labours of up to 12 hours. The occurrence of inflammatory cell infiltrates in the placenta, the membranes and the umbilical cord is not in each case due to a bacterial intra-uterine infection. The pathogenesis of these infiltrates is discussed comparing the results of the literature and this study.

Amnion

Use of biotinylated DNA probes in screening cells obtained from cervical swabs for human papillomavirus DNA sequences.

A nonradioactive DNA-detection procedure using biotinylated DNA probes in the screening of cells from cervical swabs for DNA sequences homologous to human papillomavirus (HPV) DNA was tested. This alternative DNA-detection method yielded results comparable to those obtained with radioisotope-labeled DNA probes in 32 cases tested. This procedure obviates the special precautions required for radioisotope materials. Accordingly, this technique can be made available to many laboratories, and conclusive evidence as to the relation of HPV infection to cervical cancer may thus be accumulated.

Biotin

[Conceptual basis of rehabilitation of patients with stroke].

The authors describe the basis of the current concept of rehabilitation of patients with stroke. This concept is based on recent neurophysiological findings about the processes of information, learning, and memory. This indicates that the plasticity of cerebral structures depends especially on the possibilities either to rebuild or to compensate for destroyed structures with programs of rehabilitation. A comparison is given of 101 stroke patients rehabilitated according to a conventional program and the better results for 295 stroke victims rehabilitated according to a more modern rehabilitation program. Another investigation showed, as an example of the Babinsky phenomenon, that stroke patients can develop the ability to suppress. The results and dynamics of rehabilitation of stroke are an encouragement to continue researching new ways for more effective rehabilitation.

Aged

[Social sequelae and problems following apoplexy].

162 patients with stroke (cerebrovascular accident) were investigated of some social problems. The patients were treated in two internal clinics or in a rehabilitation center for stroke-patients. The assessments were accomplished in 30 months after clinical treatment. The average of age was 69 years. The percentage of women was 61%. The majority of patients lives in own flats, 12% in a nursing home. The furniture of flats, was often not approximated for disabled persons. The care almost was undertaken through relatives. More institutional support could be helpful in few cases. Help was wished in according to conditions of flats, meals on wheels, programs for self-activities, references to nursing, technical helpings and transportation services. These investigations suggest that the families are an important factor in rehabilitation of stroke. They need social and psychological support. The attitude of family determinated essential the prognosis of rehabilitation.

Activities of Daily Living