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Biomedical subjects

C X Wang

Publications and source records attributed to C X Wang.

At least 109 records · Page 6Linked to original sources
PubMed1985

Induction of colon cancer in inbred Syrian hamsters by intrarectal administration of benzo[alpha]pyrene, 3-methylcholanthrene and N-methyl-N-nitrosourea.

Large bowel neoplasms were induced in male Syrian hamsters of the inbred strain BIO15.16 by intrarectal instillation of benzo[alpha]pyrene (BP), 3-methylcholanthrene (3-MC) or N-methyl-N-nitrosourea (MNU). Groups of hamsters were given 0.8 mg BP once weekly for 30 weeks, 0.8 mg 3-MC twice weekly for 30 weeks, or 0.8 mg MNU once weekly for 15 weeks. The experiment was terminated after 1 year. The incidences of colon neoplasms were 6% with BP exposure, 20% with 3-MC and 95% with MNU. The colon neoplasms induced by BP and 3-MC were mostly adenocarcinomas. In the group given MNU, adenocarcinomas were also produced but a substantial incidence of squamous cell carcinomas was found. These results demonstrate that the colonic mucosa of this strain of hamster is quite susceptible to cancer induction.

Animals↗
PubMedDate not supplied

Fractionation of heavy metals in surface sediments of Taihu Lake, East China.

The BCR (European Communities Bureau of Reference) three-step sequential extraction procedure was applied to fractionate heavy metals in the sediment of Taihu Lake. For the determination of total metal concentration of the sediments, sample digestion was achieved by using HF/H2O2/HNO3 (2/1/1) acid mixture in a microwave-irradiated closed vessel system. The concentrations of Cd, Ni, Cr, Zn, Cu and Pb in various extracts solutions were analyzed by Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES). The results obtained from the BCR three-step sequential extraction indicated relatively high mobility of Zn, Cu, Pb and Ni in the sediments while Cd and Cr were poorly mobile. Enrichment of heavy metals was found in the sediments collected in the northern parts of Taihu Lake. In the sediments collected in the southern and western sides of the Lake, heavy metal concentrations were relatively low. The relationship between total organic carbon (TOC) and heavy metals concentrations in the sediments is discussed.

Carbon↗