Biologic activity of adriamycin (NSC-123127) in microbial systems.
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Antibiotics, Antineoplastic↗
Biomedical subjects
C Woolley
Publications and source records attributed to C Woolley.
Azotomycin (NSC-56654): biologic fate in mice and man.
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Amino Acids↗
Microbiological assay and tissue distribution of beta-thioguanine deoxyriboside in mice.
A sensitive, precise microbiological assay has been developed for the determination of tissue distribution of beta-thioguanine deoxyriboside, a new antitumor agent.
Animals↗
5-azacytidine: microbiological assay in mouse blood.
A 6-chloropurine-resistant strain of Escherichia coli has been used to develop a microbiological assay for the estimation of 5-azacytidine distribution in mouse tissues.
Animals↗
Pseudourea, 2,2'-(9,10-anthrylenedimethylene) bis-(2-thio-, dihydrochloride) dihydrate: microbiological assay and tissue distribution studies in mice.
A microbiological assay for pseudourea, 2,2'-(9,10-anthrylenedimethylene)bis-(2-thio-, dihydrochloride) dihydrate (NSC 56054), a new anticancer agent, has been developed and tissue distribution studies in mice have been performed.
Animals↗
Modification of radiation damage of bacteria by folic acid antagonists.
Pittillo, Robert F. (Southern Research Institute, Birmingham, Ala.), Mary Lucas, Robert T. Blackwell, and Carolyn Woolley. Modification of radiation damage of bacteria by folic acid antagonists. J. Bacteriol. 90:1548-1551. 1965.-The folic acid analogues, 2,4-diamino-6-methylpteridine, amethopterin, and aminopterin, have been found to sensitize certain bacteria, especially Escherichia coli, to the lethal action of ionizing irradiation. Data are presented which indicate that (i) the compounds must be present during the irradiation period for maximal sensitization to be observed, (ii) the sensitizing effect can be nullified by cysteine or cysteamine, (iii) the sensitizing effect occurs in a number of diverse bacterial genera, and (iv) folic acid neither sensitizes bacteria to irradiation nor prevents the sensitization caused by these antifolic agents.
Aminopterin↗
Disposition of arabinosylcytosine (NSC-63878) and 6-THIOGUANINE (NSC-752) in solid L1210 leukemia tumor-bearing mice.
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Animals↗
Microbiological assay and tissue distribution of mithramycin (NSC-24559) in mice.
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Animals↗