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Biomedical subjects

C Wennmo

Publications and source records attributed to C Wennmo.

21 records · Page 2Linked to original sources

Velocity patterns of rapid eye movements.

The peak velocities of saccades and fast phases of nystagmus were examined and compared in 20 healthy subjects. The peak velocities of both types of eye movements increased with increase of amplitudes. The saccades were found to be fastest in light, slower in darkness and slowest behind closed eyelids. The peak velocities of the quick phases of optokinetic and of vestibular nystagmus were found to be the same. Fast phases of optovestibular (optic as well as vestibular stimulation) nystagmus produced significantly higher peak velocities than the two others. At the same amplitude and during the same visual conditions the saccades were significantly faster than any type of fast components of nystagmus. The difference in velocity between voluntary and reflexive eye movements is possibly related to differences in antagonistic activity during these eye movements, but also to specific synaptic events during the voluntary action.

Adult↗

Eye movements in brainstem lesions.

The eye movements of 10 patients with brainstem lesions were examined, using an electro-oculo-graphic technique. An analysis was made of the responses in the following tests: smooth pursuit, saccade, rotation, optokinetic, optovestibular and caloric. Chief interest was directed towards the peak velocity. The results were compared with the corresponding velocities in 20 normal subjects. In the same patient, one or several types of eye movements could be normal, while others were pathological. In the whole group, voluntary eye movements (smooth pursuits and voluntary saccades) were more vulnerable than reflexive ones (nystagmus). Next to the smooth pursuit test and the voluntary saccade test, the optovestibular test was the most sensitive in discriminating patients with brainstem lesions from normal subject.

Adolescent↗

Vestibular neuronitis. A clinical and electro-oculographic analysis.

Thirty patients, primarily diagnosed as having vestibular neuronitis, were investigated with a test battery consisting of neuro-otological, neuro-ophthalmological, neurological examinations and electro-oculography. Initial routine examination failed to reveal involvement of structures outside the vestibular nerve, whereas neurological evaluation and analysis of the cerebrospinal fluid indicated an intrinsic central nervous system (CNS) disorder in 6 cases. The electro-oculographic analysis revealed abnormalities supporting a 'central' cause of the vertigo in 12 cases. Altogether 13 patients showed signs of a possible intrinsic CNS disorder. Consequently, although routine examination may indicate a diagnosis of vestibular neuronitis, the patient concerned frequently has signs of an intrinsic CNS disorder and not a disorder of the peripheral nerve.

Adult↗