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Biomedical subjects

C Weissmann

Publications and source records attributed to C Weissmann.

At least 199 records · Page 11Linked to original sources
PubMed1970

The nucleotide sequence at the 5'-terminus of the Q RNA minus trand.

The sequence of the first 52 nucleotides at the 5'-end of the Qbeta minus strand has been determined and found to be complementary in an antiparallel fashion to the 3'-terminal region of the Qbeta plus strand. There are few similarities between the corresponding sequences of Qbeta plus and minus strands; however, both have a hydrogen-bonded loop close to the 5'-end. The sequence of the 3'-terminal region of the plus strand was deduced: there are no termination signals within the last 32 nucleotides. A notable homology exists between the 3'-ends of Qbeta and R17 RNA.

Adenine Nucleotides↗
PubMed1970

Location of the coat cistron on the RNA of phage Q-beta.

A new approach for the localization of a cistron on a phage RNA has been developed. The coat protein cistron of phage Qbeta was found to begin between the 1100th and 1400th nucleotide from the 5' terminus of Qbeta RNA and therefore lies in the middle of the genome.

Binding Sites↗
PubMed1967

Replication of viral RNA: RNA synthetase from Escherichia coli infected with phage MS2 or Qb.

An RNA synthetase is formed in Escherichia coli after infection with bacteriophages containing RNA. Specific annealing techniques revealed that, from the very outset of the reaction in vitro, the partially purified enzyme-template complex synthesizes parental-type plus strands, namely, MS2-RNA when isolated from cells infected with MS2 phage and Q(beta)-RNA in the case of cells infected with Q(beta) phage. This is in contrast to the situation found with Q(beta) replicase primed with Q(beta)-RNA, where the initial product is the complementary strand.

Carbon Isotopes↗