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Biomedical subjects

C Ward

Publications and source records attributed to C Ward.

At least 253 records · Page 14Linked to original sources
PubMedDate not supplied

Comparison of the performance of superflow (5F) and conventional 8F catheter for cardiac catheterization by the femoral route.

In order to determine whether the use of a smaller catheter would allow day-case cardiac catheterization by the femoral route, the performance of the Superflow (5F) and the 8F catheters was compared in 34 adults who underwent left ventriculography and coronary angiography. As shown by the significantly lower fluoroscopy time [2.8 +/- 1.2 min vs 4.5 +/- 2.7 min, (m +/- SD), p = 0.027] the 8F catheter was more maneuverable than the Superflow (5F) catheter. Poor left ventriculograms were obtained in a higher proportion of patients in whom the Superflow (5F) catheter was used. There was no significant difference in the time to achieve hemostasis at the puncture site in the two groups of patients (13 +/- 5 min vs 10 +/- 3 min, p = 0.09). It is concluded that the use of the Superflow (5F) catheter confers no advantage, while it is associated with longer screening time and poorer left ventriculograms.

Adult↗
PubMedDate not supplied

Primary intraventricular cardiac tumors in children: contemporary diagnostic and management options.

We reviewed the intraventricular cardiac tumors presenting at our institution between 1985-1991, studying the presentation, modes of investigation, and evidence of hemodynamic compromise. Thirteen patients presented with intraventricular tumors during the study period. Two of the tumors were rhabdomyosarcomas, one was a myxoma, and 10 were rhabdomyomas. All patients were evaluated with two-dimensional and pulsed Doppler echocardiography and B-color imaging was undertaken in three patients. Four patients presented for elective scans to complement investigations for tuberous sclerosis, seven patients had cardiac symptoms, and two patients presented prenatally. Obstruction to intracardiac flow was present in five patients. Two patients had the tumor excised and one had an open biopsy of the tumor. One patient had an transvascular biopsy at cardiac catheter. Early detection of cardiac tumors is increasing, particularly rhabdomyomas. With fetal echocardiography, more patients should come to attention prenatally. B-color may be useful addition in assessing cardiac tumors, aiding detection and definition of intramural lesions.

Child↗
PubMedDate not supplied

Echocardiographic load-independent indices of contractility in children and adolescents with type I diabetes: effect of metabolic control and insulin on left ventricular performance.

A case-control study was carried out in a tertiary referral teaching hospital to evaluate left ventricular contractility in children and adolescents with type 1 diabetes and to study factors influencing left ventricular contractility. Thirty-four children and young adults with type 1 diabetes (age 10.8-21.8 years) were randomly selected from approximately 400 patients of the same age range in the outpatient department and compared with 16 non-diabetic controls (age 7.3-21.2 years). The relation of end-systolic wall stress to velocity of circumferential fiber shortening as a standard deviation score (SDS) from the normal range described by Colan et al. was used to assess left ventricular contractility. In the diabetic group the effect of age, duration of diabetes, metabolic control, insulin dose, and autonomic function on left ventricular contractility were studied. It was found that the end-systolic wall stress-velocity of circumferential fiber shortening relation was not different between diabetic subjects and controls [+0.52 (SEM 0.21) vs +0.90 (SEM 0.26) SDS, p = 0.3]. In the diabetic subjects, the end-systolic wall stress-velocity of circumferential fiber shortening relation was positively correlated with glycated hemoglobin (r = 0.37, p = 0.03) and insulin dose per kilogram of body weight (r = 0.36, p = 0.04). Those two variables together explained 24% of the variability in the end-systolic wall stress-velocity of circumferential fiber shortening relation. Twenty-eight of the diabetic subjects were also assessed for cardiac autonomic function. Disturbances of cardiac autonomic function were not associated with increased contractility.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMedDate not supplied

Magnetic resonance imaging evaluation of the patellar tendon after use of its central one-third for anterior cruciate ligament reconstruction.

Magnetic resonance imaging was used to evaluate the remaining patellar tendon after its central one-third had been harvested for anterior cruciate ligament reconstruction. Twenty patients were studied at either 6 weeks, 4, 6, 9, or 18 months postoperatively. The average thickness, width, cross-sectional area, and signal intensity of the operated and contralateral non-operated tendons were calculated and compared for each magnetic resonance imaging scan. A significant increase in the thickness was noted at all periods of followup, but no change in width occurred despite the defect being closed at the time of surgery. High signal intensity was present in the early periods, which signified edema and scar tissue. Signal intensity decreased at subsequent follow-up periods until at 18 months the operated tendon appeared normal. These findings indicate that the patellar tendon has the potential to regenerate and remodel in the postoperative period.

Adult↗
PubMedDate not supplied

An observational study of intergenerational activities and behavior change in dementing elders at adult day care centers.

This study investigated whether dementing adult day care clients demonstrate consistent positive behaviors (i.e., eye contact, smiling, attentiveness, etc.) during structured, weekly activities with young children that these adults do not demonstrate during similar activities when the young children are not present. The study built on a preliminary informal study conducted in conjunction with an intergenerational adult day care project. Participants for the study were twenty-one adult day care clients who have behavioral characteristics of Alzheimer's or related disorders. The study involved five consecutive weeks of planned, structured music activities prepared by a musical therapist as part of the regular intergenerational activities of the adult day care center. The same activities were repeated twice in the same day at each site, once with children present and once without them present. Two fixed videotape cameras recorded client behaviors in three-minute segments. Scoring was completed by trained, "blind" scorers. The scorers tallied positive behaviors by individuals for randomly selected ten-second segments of the taped intervals. Sessions with and without children were compared using non-parametric tests. Categories of behaviors were compared and specific observed behavioral changes were reported.

Aged↗