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Biomedical subjects

C W Hanke

Publications and source records attributed to C W Hanke.

At least 73 records · Page 4Linked to original sources
PubMed1989

Cryostat use and tissue processing in Mohs micrographic surgery.

Information of cryostat use and reliability was collected from 130 members of the American College of Mohs Micrographic Surgery and Cutaneous Oncology. The Damon IEC International cryostat was utilized by 38% of the survey participants, followed by the Reichert Histostat (18%) and the LabTek/TissueTek (13%). Data were also collected on methods of frozen-section embedding and technical training.

Cryosurgery↗
PubMed1989

Cancer of the scalp.

Carcinomas on the scalp have a tendency to recur following traditional treatment. Their management is often difficult because of the extent of the tumor and the unique anatomy of the area. In order to maximize cure rates for complicated carcinomas, Mohs micrographic surgeons and other surgical specialists have formed interdisciplinary treatment teams. Resection of bone, parotid/facial nerve dissection, and neck dissection are often necessary. Interdisciplinary cooperation in the treatment of skin cancer leads to maximal utilization of expertise and is a major advance in cancer treatment.

Adult↗
PubMed1988

Safety of liposuction: a review of 9478 cases performed by dermatologists.

Complications and methods of anesthesia were reviewed in 9478 patients who had undergone liposuction surgery often in several areas. Seventy-one percent of the patients were treated under local anesthesia and the overall level of complications was extremely low. The results of the survey reflect the large number of liposuction procedures that are being performed by dermatologists with a high degree of patient safety.

Adolescent↗
PubMed1988

Neoplasms of the conchal bowl: treatment with Mohs micrographic surgery.

Thirty-four patients with tumors in the conchal bowl were treated with Mohs micrographic surgery. Twenty-six patients had basal cell carcinoma and 8 patients had squamous cell carcinoma. Thirty-three of 34 patients achieved a tumor-free margin during initial therapy. All patients remain free of recurrence and metastasis at an average follow-up period of 2.9 years. Thirty-three of 34 patients were allowed to heal by second intention. Only one patient required reconstruction to avoid stenosis of the external auditory canal.

Adult↗
PubMed1988

Allergic necrotizing eosinophilic granulomatosis.

Allergic necrotizing eosinophilic granulomatosis (ANEG) is a rare entity characterized by peripheral eosinophilia, hepatosplenomegaly, dyspnea, and lymphadenopathy. An unusual patient with ANEG is described in which the presenting feature was an extensive granulomatous lesion of the face. The patient's condition progressively deteriorated despite multiple therapies, and she finally succumbed to her disease.

Biopsy↗
PubMed1987

Blast tattoos resulting from black powder firearms.

Blast tattoos occur when fragments of gunpowder are propelled into the skin during a firearm discharge. This unusual type of injury is often associated with accidents involving replica firearms. Some of the more superficially embedded powder fragments may be removed with dermabrasion; however, deeper fragments may cause permanent tattooing. Blast injuries to the face also have the potential of causing permanent eye injury.

Adult↗
PubMed1987

Mycobacterium kansasii infection with multiple cutaneous lesions.

Mycobacterium kansasii infections of the skin are rarely seen and present variable clinical and histopathologic features. Laboratory identification of the organism is essential for proper diagnosis and selection of appropriate antimycobacterial medications. Antituberculous drugs are the standard treatment; however, therapy with tetracycline or minocycline is a provocative alternative.

Female↗
PubMed1987

Treatment of multiple facial neurofibromas with dermabrasion.

Three patients with multiple facial neurofibromas were treated by dermabrasion with good cosmetic results. Wound healing was entirely normal and no complications were observed. There was no evidence of accelerated regrowth of tumors during follow-up.

Adult↗
PubMed1987

Repair of surgical defects.

Basic skills in elliptical excision are essential for success in dermatologic surgery. Once the elliptical excision has been mastered, the practitioner should progress to variations on the ellipse. These include "curving" the incision, M-plasty, A-to-T closure, O-to-Z closure, and subcutaneous island pedicle flaps. When one of these methods will not suffice, a local flap or a full-thickness skin graft is often a good alternative.

Humans↗
PubMed1986

Large keratoacanthomas in difficult locations treated with intralesional 5-fluorouracil.

Keratoacanthoma is a benign tumor; however, it may cause massive destruction of normal tissue during its rapid growth phase. Intralesional 5-fluorouracil (5-FU) has been shown to be an effective treatment for keratoacanthoma. We have successfully treated five patients with large keratoacanthomas in difficult locations. There have been no recurrences during follow-up periods ranging from 18 to 45 months. Intralesional 5-FU may be ineffective for keratoacanthomas that are not rapidly proliferating.

Adult↗
PubMed1986

Atypical keloids after dermabrasion of patients taking isotretinoin.

Six patients underwent dermabrasion while on or having recently completed isotretinoin (Accutane) therapy. All patients developed keloids in atypical locations; the keloids eventually responded to topical or intralesional steroid therapy. Retinoids have a modulatory effect on connective tissue metabolism, including suppression of collagenase, which may enhance keloid formation. Dermabrasion should be delayed in those patients taking or recently on isotretinoin therapy.

Acne Vulgaris↗
PubMed1986

Quantitative assessment of burn injury in porcine skin with high-frequency ultrasonic imaging.

Early excision and grafting of full thickness burns has been shown to decrease morbidity and mortality. Errors made in assessing acute burn depth are common and result in prolonged hospitalization in expectant healing of full-thickness burns and in unnecessary excision and grafting of potentially regenerative partial-thickness burns. High-frequency ultrasonic imaging may be a noninvasive, convenient means of quantitating burn depth. A depth analysis system for imaging burned skin was developed using a high-frequency 18.5 MHz (nominal 25 MHz) pulse-echo ultrasound system with a longitudinal resolution of 86 mu. Five adult mini-swine (15 kg) were burned with a temperature-(190 degrees C) and pressure-controlled (236 g/cm2) burning iron. A series of burn durations (1-45 seconds) was used to inflict partial- and full-thickness burns of various depths. Ultrasonic scans of the acutely excised burns were performed across the lateral margin of the burn, including adjacent normal skin to serve as control. Direct histologic comparison was made with each scan plane. Average burn and normal skin depth measurements were made by independent observers for 34 scans and corresponding histologic sections. A significant correlation was achieved between burn depth and percent burn (burn depth/adjacent normal skin depth) as measured by ultrasound and histology (R = 0.90, t = 11.2, P less than .001).

Animals↗