Hypocalcemic effect of pentagastrin and related gastrointestinal hormnal peptides in the rat.
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Biomedical subjects
Publications and source records attributed to C W Cooper.
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Administration of a small dose of pentagastrin, a synthetic pentapeptide containing the biologically active portion of the native hormone gastrin, results in a marked, rapid, transitory increase in thyrocalcitonin secretion in the pig. Gastrin or a related gastrointestinal peptide may be important in the physiological secretion of thyrocalcitonin, such as that which occurs when calcium salts are introduced into the gastrointestinal tract.
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