Epidemiology of naturally occurring feline uroliths and urethral plugs.
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Animals↗
Biomedical subjects
C W Clinton
Publications and source records attributed to C W Clinton.
Leydig-Sertoli cell tumour in the postmenopausal female. A case report.
A patient with a Leydig-Sertoli cell tumour of the ovary is described. This rare lesion coexisted with three other primary neoplastic lesions, namely an adenocarcinoma of the colon, an ovarian fibroma, and leiomyomas of the uterus. A discussion of the unusual ovarian lesion and a short review of the literature are presented.
Adenocarcinoma↗
Mineral composition of urinary calculi from miniature schnauzer dogs.
The mineral composition of 150 calculi from the urinary tracts of Miniature Schnauzer dogs was determined by qualitative and quantitative methods. Struvite was the predominant mineral in 92% of the calculi. Other calculi contained predominantly apatite, calcium oxalate, ammonium urate, or silica. Most calculi were from the urinary bladder or urethra, or both. Four were from the renal pelves. Struvite calculi were more frequently encountered in females than males. The mean age of the dogs at the time of detection of calculi was 4.8 years. Qualitative analysis failed to detect some minerals that were identified by quantitative analysis.
Animals↗
Reproductive tract calculi, their induction, age incidence, composition and biological effects in Balb/c Crgl mice injected as newborns with estradiol-17 beta.
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Age Factors↗
Acetohydroxamic acid: clinical studies of a urease inhibitor in patients with staghorn renal calculi.
The hydrolysis of urea by the bacterial enzyme urease pathologically increase urinary ammonia, bicarbonate, carconate and alkalinity. These factors contribute to the formation of urinary stones and to the virulence of bacteria. Acetohydroxamic acid, a potent inhibitor of urease, has been administered to 23 patients with staghorn renal calculi and urea-splitting urinary infection. Urinary ammonia and alkalinity has been reduced in every patient. A dose of 1.0 gm. acetohydroxamic acid daily has been well tolerated and effective for 2 to 12 months, even in patients with impaired renal function.
Ammonia↗