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Biomedical subjects

C Vosa

Publications and source records attributed to C Vosa.

34 records · Page 2Linked to original sources

Aortic valve homografts in the surgical treatment of complex cardiac malformations.

From April of 1968 to March of 1983, the surgical treatment of complex congenital cardiac malformations requiring an extracardiac conduit for their correction was performed with aortic valve homografts or aortic valved homograft conduits sterilized and preserved in our hospital. Our experience concerns 93 patients in whom a total of 103 aortic valve homografts were implanted. Ages of the patients ranged from 7 months to 36 years (mean 11.6 years). The aortic valve homografts were used from the right atrium to the pulmonary arteries or right ventricle (right atrium-dependent conduit), from the venous ventricle to the pulmonary arteries (ventricle-dependent conduit), or in the pulmonary orifice and in the superior and/or inferior venae cavae. There were 25 early and nine late deaths (36.5%), none of them related to the aortic valve homograft. The clinical follow-up of the 59 survivors (1 month to 15 years, mean 4.3 years) evidenced neither dysfunction of the aortic valve homograft nor thromboembolism or hemolysis; 93% of the patients are in New York Heart Association Class I or II. Control cardiac catheterization in 53 patients evidenced a pressure gradient in only 14 ventricle-dependent conduits. In seven patients with serial control catheterizations after 5 to 10 years, the pressure gradient had not increased.

Adolescent↗

Pre-and postoperative Tc 99m scanning in monitoring pulmonary perfusion in the tetralogy of Fallot.

Angiocardiopneumographic scanning with Tc 99m was used in pulmonary perfusion and intracardiac shunt before and after radical corrective surgery of the tetralogy of Fallot. The study was carried out on 25 patients with the tetralogy of Fallot undergoing radical treatment with infundibular patch. Preoperative scanning has shown increased thickening of right ventricle and contemporary injection of pulmonary artery and aorta, the latter with a much higher radioactivity; the obstruction to the right flow was not clearly defined with respect to morphology and function, pulmonary perfusion has shown an extremely poor radioactivity and prolonged duration. Scanning following surgical treatment showed normal right and left phase and absence of residual shunts. Captation of marker in the lungs was always complete. Such data illustrate the many advantages gained by the use of non invasive diagnostic procedures in cardiology and "the first pass technique" in the evaluation of results of surgical treatment.

Aorta↗

[Cold agglutinins in a cardiosurgical patient: a successfully operated case].

A technique is described for providing myocardial protection with cold cardioplegia in a patient with cold autoagglutinins. The operation was done in normothermia and the coronary system was perfused with a normothermic (+37 degrees C) NaCl 0,9% solution to remove the blood before in it introducing the cold (+4 degrees C) cardioplegic solution. With this technique, the patient underwent an uneventful operation to relieve right ventricular-outflow stenosis operation.

Agglutinins↗

Ostium secundum atrial septal defect: is it a minor cardiac lesion?

One-hundred-ten cases of ostium secundum atrial septal defect, surgically treated from 1975 to 1980, are reported. The early postoperative deaths were two (1.81%), both due to acute left ventricular failure. In the postoperative complications, along with arrhythmia, is left ventricular failure markedly represented (4 cases). These observations can be suggestive of a major role of left ventricular function in the natural course of atrial septal defect and its treatment, and could emphasize the importance of preoperative left ventricular study, effective intraoperative myocardial protection, and early operation (age two years), in order to prevent left ventricular involvement and failure.

Adolescent↗

[Our experience in treatment of the inhibition of demand pacemaker by muscle potentials (author's transl)].

The inhibition of demand pacemakers by muscular potentials is rarely described in the literature. The Authors have found an interference of the pectoralis muscle's electric activity with pacemakers in 4 patients suffering from occasional faints. Extending this study to a group of 10 asymptomatic electrostimulated patients, pacemaker's inhibition by sub-maximal contraction of pectoralis major muscle has been found in 9 of them. The 4 symptomatic patients have been operated displacing the battery near the sternum. The poor thickness of the pectoralis muscle's fibres suggested the treatment. The controls performed from 2 to 8 months respectively have shown disappearance of the symptoms.

Action Potentials↗

[Demand pace-maker for the treatment of carotid sinus syndrome (author's transl)].

This is a report of a case of carotid sinus hypersensitivity treated with an endocardial demand ventricular inhibited pacemaker. With this modern form of therapy of carotid sinus hypersensitivity we have obtained in the case presented a complete resolution of lipothymic attacks due to complete atrioventricular (A-V) block secondary to carotid sinus stimulation. The patient discharged from the hospital after seven days from the implantation of the pacemaker has been symptom free at a control after eight months.

Carotid Artery Diseases↗

Ultrastructural pathology of pediatric myocardium in acute ischemia: bioptic study before and after treatment with cardioplegic solution.

Protecting the myocardium from the risk of acute ischemia during heart surgery is still an unsolved problem; the problem is even more open and more pressing in pediatric heart surgery. To meet this greater risk it is advisable to use a cardioplegic solution with a composition that is better suited to the particular morphofunctional conditions of the myocardium in the child, i.e., a solution offering greater protection. To this purpose the authors experimented with Celsior cardioplegic solution during heart surgery in children to evaluate the efficacy compared to the standard St. Thomas solution. In this comparative study 15 children were treated with Celsior cardioplegic solution and 15 others with St. Thomas cardioplegic solution. Each patient underwent 2 biopsies of the myocardium, the first before cardioplegic treatment and the second immediately after reperfusion. In both groups, focal lesions involving both the cardiomyocytes and the vascular-stromal structures were randomly found. The former had undergone a necrotic-regressive process with changes in the myofibrils and the mitochondria. The vascular-stromal structures showed changes in the permeability of the capillary endothelia, with interstitial edema. The results show the lesions to be similar in the 2 groups both on a quality and quantitative level.

Capillary Permeability↗