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Biomedical subjects

C Verougstraete

Publications and source records attributed to C Verougstraete.

At least 37 records · Page 2Linked to original sources

[Diabetic retinopathy and pregnancy].

Pregnancy is an important independent risk factor for diabetic retinopathy. This risk is increased with diabetes duration, bad metabolic control, diastolic hypertension, renal disease, anemia, rapid reduction of Hb A1c level and severity of baseline retinopathy. Retinal examination must be done at onset of pregnancy and every 3 months thereafter until 3 months after delivery. Eye fundus will be controlled every month if retinopathy occurs in patients with risk factors. Laser treatment is as efficient during pregnancy as usually.

Diabetic Retinopathy↗

[Chorioretinal lymphoproliferative disorder induced by Epstein-Barr virus in lung transplantation].

The Epstein-Barr virus (EBV) is the causative factor of the posttransplant lymphoproliferative syndromes. Some ocular cases were described. We report the case of a lung-transplanted 59 year old man who presented a chorioretinal lymphoproliferative syndrome. A B-cell monoclonality and numerous EBV genome copies were demonstrated in vitreous material by PCR. We suspect an intermediate stage between polyclonal lymphoproliferative syndrome and malignant lymphoma. A treatment with nucleoside analogs and immunosuppression decrease was successful. The positive clinical evolution was associated with a reduction of the EBV genome quantity.

Chorioretinitis↗

[Massive subretinal hemorrhage in the course of age-related macular degeneration: preliminary study].

We retrospectively studied 58 eyes with a subretinal haemorrhage > or = 5 disc areas related to age-related macular degeneration. The subretinal new vessels which caused the haemorrhage were occult or mixed except in 2 cases of well-defined new vessels where the haemorrhage appeared after a trauma. A pigment epithelium detachment was present in 1/3 of the cases before the haemorrhage. 36% of the patients had one or more important haemorrhagic recurrences. In 32% of the cases, the visual acuity before the haemorrhage was > or = 4/10. The final evolution resulted in an important fibroglial and atrophic central scar with a dramatic loss of visual acuity (85% VA < 0,1).

Aged↗

First microangiographic abnormalities in childhood diabetes--types of lesions.

An analysis by fluorescein angiography of the first signs of retinopathy in 161 diabetic children showed that microaneurysm-like spot dilatations, microaneurysms, focal capillary dilatations, leakage, generalized capillary dilatations, retinal hemorrhages, areas of capillary non-perfusion and capillary remodelling, in decreasing order of frequency, were features of the onset of retinopathy. However, microaneurysm-like spot dilatations and both focal and generalized capillary dilatations were considered to be too subjective for use in further quantitative analysis. Retinopathy was not found in children less than 12 years of age and was detected only after at least 3 years of diabetes. The mean duration of diabetes before the occurrence of the first lesions in 118 affected eyes was 8.2 years. The mean age at which lesions occurred was 16.4 years. Although capillary non-perfusion was rarely an initial lesion, occurring after a longer duration of diabetes and at a later age than the other lesions, no significant difference could be found between the various types of lesions for either the patient's age at their onset or the duration of diabetes. The type of initial lesion was also unrelated to sex, age at the onset of diabetes, or metabolic control.

Adolescent↗

[Macular edema in arterial hypertension].

Acute arterial hypertension causes 3 types of fundus anomalies: hypertensive retinopathy, hypertensive choroidopathy and hypertensive optic neuropathy. Hypertensive retinopathy and optic neuropathy are characterised by retinal and optic disc capillary and precapillary occlusions, and a rupture of the inner hemato-retinal barrier resulting in retinal edema. Hypertensive choroidopathy is characterized by areas of choriocapillaris occlusion resulting in necrosis of the pigment epithelium which causes a rupture of the outer hemato-retinal barrier and retinal edema.

Choroid Diseases↗

[Macular edema in retinal vein occlusion].

Venous occlusion causes retrograde intravascular hyperpression resulting in a rupture of the inner hematoretinal barrier and sometimes in capillary occlusions. The various clinical types of venous thrombosis which result from various degrees of intravascular hyperpression have different prognoses. The laser treatment of macular edema secondary to venous occlusion is recommended under certain conditions.

Humans↗

[Retinal telangiectases].

Retinal telangiectases have 3 main clinical forms: Leber-Coats disease, Adult Coats disease and parafoveal telangiectasia. Clinical characteristics, evolution and modes of treatment will be reviewed.

Adolescent↗

[Arterial macro-aneurysm].

Retinal macroaneurysms cause visual symptoms either by hemorrhage, by exsudation or by arterial occlusion. Laser treatment shortens life duration of the macro-aneurysm and results in reabsorption of retinal edema. Direct coagulation of the macroaneurysm should be avoided so as not to enhance the risk of arterial occlusion.

Aneurysm↗

Ocular toxocariasis: a presumed case of peripheral granuloma.

We report a case of peripheral Toxocara granuloma in a young boy of 17. Of the 3 forms of ocular toxocariasis, macular granuloma, endophthalmitis and peripheral granuloma, the latter is the least common and is characterized by the retention of relatively good vision. A differential diagnosis was performed between an intraocular foreign body encapsulated in fibroglial tissue, toxoplasmic retinochoroiditis, retinoblastoma, intermediate uveitis and toxocariasis. Fluorescein angiography showed not only some neovascularizations at the level of the peripheral granuloma but also manifestations of inflammatory reactions at the level of the posterior pole, i.e. diffuse leakages from retinal capillaries and parietal staining of some venous segments. Among the various laboratory tests, the most significant are eosinophilia, IgE concentration and detection of specific antibodies in serum as well as in aqueous humour.

Adolescent↗

[What resuscites child resuscitation?].

At the crossroads of the psychological and the somatic course, a symptom appears as a crisis for the patient (the child), his environment and the medical and paramedical staffs who are in contact with him. Starting concrete situations, this article describes what happens when the family is confronted with the reanimation of a child.

Child↗