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Biomedical subjects

C Vaillant

Publications and source records attributed to C Vaillant.

78 records · Page 5Linked to original sources
PubMed1965

[Toxic tremors].

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Humans↗
PubMedDate not supplied

[Blood levels of homocysteine by high pressure liquid chromatography and comparison with two other techniques].

Cardio-vascular diseases are the most common cause of death in industrialized countries. A new marker has emerged among offending risk factors in the past few years: homocysteine. This sulphured amino-acid is an important intermediate in transsulphuration and remethylation reactions of methionine's metabolism. We proposed to evaluate a home made method of determination for this parameter by high performance liquid chromatography (HPLC) and to compare it to fluorescence polarization immunoassay technique (FPIA) and to gaz phase chromatography (CG-SM). This method associated with good sensibility and precision remain much less expensive than FPIA technique.

Acetylcysteine↗
PubMedDate not supplied

[Acute organophosphorus pesticide poisoning and cholinesterases activities].

Suicides attempts with an organophosphate pesticide still occur in Brittany, an agricultural French area. The acute poisoning due to this nerve agent, responsible for the inhibition of the cholinesterases enzymes, is severe and can be fatal. The diagnosis is based on the decrease of cholinesterases activity, an assay which has been performed because of the patient context. The measurement of butyrylcholinesterases activity in emergency guarantees an appropriate and rapid management of the patient in order to rapidly regenerate cholinesterases. Even if the decrease level of butyrylcholinesterases activity does not give a significant prognostic value, its follow-up with time indicates the efficacy of the treatment and the gradual remission. In routine the measurement of acetylcholinesterase activity is more useful for the biological follow-up of subjects exposed to organophosphate phytosanitary compounds.

Acute Disease↗