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Biomedical subjects

C Vago

Publications and source records attributed to C Vago.

At least 19 recordsLinked to original sources

Cognitive and behavioural effects of migraine in childhood and adolescence.

Since cognitive and behavioural characteristics of paediatric migraine sufferers have yet to be adequately defined, in this study we assessed the effect of migraine on the interictal functioning of children and adolescents by comparing the performance of two patient groups, 17 migraine sufferers with aura (MA) and 31 without aura (MoA) and by correlating the duration of the disorder, the frequency of attacks and interictal period with neuropsychological and behavioural findings. Both patient groups had cognitive performance within normal range except for a significant delay in the reaction time (RT) task. Both MA and MoA revealed a behavioural phenotype characterized by internalizing problems on Child Behaviour Check List (CBCL) scales. Slower RT to simple visual stimuli may be an early sign of a subclinical neuropsychological dysfunction, significantly correlated with the frequency of headache attacks and interictal period. The lack of a control group and other methodological limitations, such as patient selection bias and unadjusted P-value for multiple testing, make it difficult to give this finding a clearcut meaning. Further studies are needed on larger samples compared with a control group.

Adolescent↗

Unilateral frontal lobe epilepsy affects executive functions in children.

Very few studies to date have investigated the neuropsychological changes detectable in children suffering from frontal lobe epilepsy (FLE). The aim of the present study was to assess the effects of FLE on cognitive and executive functions in childhood. The sample includes 17 children with a frontal epileptogenic focus (10 right and 7 left), with no evidence of anatomical brain damage. These subjects were assessed by means of a battery of tests to investigate executive functioning. The results emphasised the presence of selective impairments of frontal lobe functions without evidence of deficits in global intellectual functioning. No side-specific deficits were detected, while an earlier onset of epilepsy and the duration of the disorder, but not the seizures frequency, were found to correspond with more severe deficits in some specific frontal lobe functions.

Adolescent↗

[Effect of delta-endotoxin of Bacillus thuringiensis israëlensis on biochemical functional relationships in Diptera Aedes aegypti].

A study of the action of very low doses of the delta-endotoxin of Bacillus thuringiensis israëlensis on the larvae of Aedes aegypti (Diptera) gave evidence for peculiar properties of the dose/effect relations based on the variations of the regression slopes of functional relationships between the pairs cysteine/serine and fatty acids/histidine, by contrast with the pair fatty acids/glucose which exhibited a classical shaped relation. This indicates "crypto-toxicological" processes, not lethal by themselves and without pathological symptoms, but able to initiate "pathogen-chaining" mechanisms leading, at the end, to a lethal secondary syndrome.

Aedes↗

[Viral infection in a platyhelminth parasite].

In parenchyme cells of the parasitic Plathelminthe Diplectanum aequans virus-like cytoplasmic particles were observed. Their formation is noted in virogenic areas and they are often gathered in regular geometric arrangements. The infected cells show important lesions.

Animals↗

[Endocellular pathogenic bacteria in the monogenean Euzetrema knoepffleri].

Intracellular bacteria (Rickettsia) are found in the Monogenean Euzetrema knoepffleri, vesicular endoparasite of the Amphibian Euproctus montanus (Urodela). In some conditions, they cause cytoplasmic damage in the host tissues, which demonstrates their pathogenicity. These bacteria are present during all the stages of the life-cycle of E. knoepffleri. Their transmission from one generation to the next occurs through the gametes.

Amphibians↗

Parvoviridae.

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Parvoviridae↗

[Tumor formations and cell proliferation in invertebrates].

Critical analysis of the present status of invertebrate oncology through an appreciation of data relative to the various origins of tumors : spontaneous formations, cell proliferations induced by viruses, so-called hereditary tumors, effects of injuries induced by carcinogenic agents, irradiations or hormones on the formation of neoplasms in invertebrates. Attempts are made to interpret these data as compared with those obtained in medical and veterinary oncology. The possible direction of studies on invertebrates towards comparative oncology is considered, emphasizing the great usefulness for the medical research to study the phylogenetic development of oncogenesis.

Animals↗