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Biomedical subjects

C V Hodges

Publications and source records attributed to C V Hodges.

At least 37 records · Page 2Linked to original sources

Transpubic urethroplasty for membranous urethral strictures.

Six patients with traumatic membranous urethral strictures have undergone urethroplasty utilizing the traspubic approach with resection of a wedge of the symphysis pubis. Three patients are free of stricture, 2 required urethral dilatation in the early postoperative period only, and 1 patient requires dilation every three months. Four patients are completely continent of urine, 1 has mild stress incontinence, and 1 is incontinent because of a neurogenic bladder. This approach provides excellent exposure with minimal morbidity and allows an easy under-vision anastomosis.

Adult↗

Acute renal vein thrombosis with dextran treatment.

The case of a 35-year-old woman with active ulcerative colitis and acute left renal vein thrombosis is presented. The successful management of this patient with dextran-70 is contrasted with other modes of therapy used currently.

Acute Disease↗

Angiographic infarction of a large hypernephroma with a tissue adhesive for control of hematuria.

A case of a large inoperable hypernephroma in a 69-year-old man is presented. Recurrent life-threatening hematuria was controlled successfully by transcatheter embolization and infarction of the tumor using a tissue adhesive called isobutyl 2-cyanoacrylate. The patient remained without hematuria for 18 months until death from extensive metastatic diseases. The advantages and disadvantages of tissue adhesive as an embolization material are discussed.

Adenocarcinoma↗

The morbidity of radical prostatectomy for multifocal stage I prostatic adenocarcinoma.

During a 25-year period 33 patients with stage I multifocal prostatic adenocarcinoma underwent radical prostatectomy. Carcinoma was present in 81 per cent of the specimens. The operative mortality was 3 per cent. Pelvic recurrence, rectal injury and urethrovesical stricture each occurred in 9 per cent of the cases. Fifteen per cent of the patients were totally incontinent and 42 per cent had stress incontinence. One patient required combined retropubic and perineal approaches to remove the specimen. The safest interval between the first and the radical procedure was 6 weeks or more. The 5 and 10-year relative survival rates were 100 per cent. The best candidate for a radical prostatectomy after transurethral prostatic resection or suprapubic enucleation prostatectomy is one with a thick surgical capsule in whom the first procedure procedes the radical procedure by at least 6 weeks.

Adenocarcinoma↗

An animal model for the growth of human tumor cell lines.

Newborn rats were thymectomized at less than 24 hr of age and received antilymphocyte serum and heterologous human tumor cells. This model allows the growth of large primary tumors with a high metastatic percentage. This model may be applicable to the study of a wide variety of genitourinary tumors.

Animals↗

Ureterocolostomy. An antireflux technique.

A new antireflux ureterocolonic urinary conduit was developed and evaluated in sheep. It combined the principles of the Wallace conjoined ureterointestinal conduit with the Lich extravesical ureteroneocystostomy. The procedure accomplished the following with a single anastomotic technique: (i) joined both ureters to the intestinal stump; (ii) provided constant ureteral orifice position in the antimesenteric butt of the intestinal segment; (iii) eliminated the blind intestinal stump; (iv) prevented intestinoureteral reflux; and (v) allowed an average of 12 times the normal urinary flow rate before exceeding mean human midureteral peristaltic pressure. The projected long term animal experiments and the sound urologic surgery principles involved indicate that the procedure may soon have clinical application.

Animals↗

Testis tumor metastatic to lung: twenty-two-year survivor.

A case is presented of a twenty-two-year survivor following pulmonary resection of a solitary embryonal cell carcinoma metastasis from a primary teratocarcinoma of the testis. The literature is reviewed with regard to this problem, and the criteria for pulmonary resection of metastic lesions are presented.

Adult↗

Disseminated nocardiosis presenting as testicular abscess.

A case of a localized testicular abscess due to Nocardia asteroides in a patient on immunosuppressive therapy for a myeloproliferative disorder is reported. Subsequent fatal dissemination of the infection to the prostate, lungs, and liver occurred. This represents the second reported case of nocardiosis of the testis. Extrapulmonary forms of nocardiosis must be recognized so that appropriate treatment can be instituted prior to dissemination.

Abscess↗

Angiomyolipoma: diagnosis and treatment.

Four cases of renal angiomyolipoma are presented, 3 of which were diagnosed in non-tuberous sclerosis patients. In 1 case diagnosis was made preoperatively and in another case it was made intraoperatively, allowing for preservation of functioning renal parenchyma. The second successful kidney transplant in a patient with tuberous sclerosis and renal failure is reported. One cannot always differentiate renal angiomyolipomas from adenocarcinoma. However, if the classical angiographic findings of sacculated pseduo-aneurysms supplied by the interlobular and interlobar arteries are present non-operative observation or limited surgery with preservation of renal tissue is possible. Also, knowledge of the gross pathologic appearance and the syndrome of tuberous sclerosis will allow one to make a preoperative or intraoperative diagnosis with confidence.

Adult↗

Ureteroileourethrostomy: 16-year followup.

Ureteroileourethrostomy has been abandoned at our institution for replacement of the bladder because: 1) it compromised the cancer operation and 2) upper urinary deterioration forced conversion to ureteroileocutaneous diversion in 2 of 3 patients. The ureteroileourethrostomy may have future application if all of the prostate is removed when cystectomy is necessary for bladder cancer. The urinary retention can be satisfactorily managed with clean, intermittent self-catheterization. The hyperchloremic metabolic acidosis can be satisfactorily managed by reducing residual urine and potassium citrate administration. The upper urinary tract changes can be partially or wholely prevented with antirefluxing ureteroileal anastomoses.

Adult↗

The ureteral stump after nephroureterectomy.

Herein we review 70 cases of transitional cell carcinoma of the upper urinary tract. When complete nephroureterectomy was not performed transitional cell carcinoma developed in 30 per cent of the remaining ureteral stumps. Single incision nephroureterectomy did not include the intramural ureter in 50 per cent of the cases in which it was performed. When nephroureterectomy is selected as treatment for carcinoma of the renal pelvis or ureter a cuff of bladder, which includes the ureteral orifice, should be removed. A second incision may be required for adequate exposure.

Carcinoma, Transitional Cell↗

Renal transplantation in pediatric patients.

Thirty-five transplants have been performed in 29 children, 1 week to 16 years old. Of these patients 79 per cent are surviving from 9 months to 14 years post-transplantation. Eighteen of these patients have required different surgical procedures for transplantation than adult patients. Immunosuppressive therapy has been essentially the same as in adult patients. A striking difference between the living related donor and the cadaver donor transplant functional survival as seen in this series is unexplained at the present time. Linear growth has been good in those children who have required minimal doses of corticosteroids to maintain adequate renal function.

Acute Kidney Injury↗

Renal transplantation in cystinosis.

Three children from 6 1/2 to 10 years old received kidney allografts from their parents 2 1/2 to 4 1/2 years ago. Renal function has been stable and the patients have been doing well. Studies of renal tubular function as well as morphologic studies by light and electron microscopy, and microdissection of renal tubules fail to reveal evidence of recurrent disease in the allografted kidneys.

Biopsy↗

Non-urologic flank pain: a diagnostic approach.

Pain typical of that from the diseased reno-ureteral unit can emanate from any adjacent organ or any organ with the same innervation. It may also be the result of, or be exacerbated by, mental illness. Case examples of herniated thoracic disk, T12 neuralgia and short leg syndrome, costovertebral joint arthritis, metastatic carcinoma, myofascial syndrome and pancreatitis demonstrated the need for an orderly approach to the problem. Currently, patient screening with the Cornell medical index and the urology questionnaire allows direction of the physical examination, special radiographic and laboratory studies and psychiatric evaluations. An orderly evaluation of flank pain will prove rewarding and may prevent unnecessary urologic operations.

Adult↗

The supracostal approach to the kidney and adrenal.

Our experience with 67 supracostal approaches to the kidney or adrenal gland demonstrates that 1) the exposure was uniformly superb,2) diaphragm reapproximation was unnecessary, 3) a single pericostal suture soundly closed the intercostal space, 4) no complications could be attributed to inadequate exposure and 5) pleural entry was the most common complication. We have found the supracostal approach to the kidney and adrenal to be staisfactory and recommend it to others.

Adrenalectomy↗

Suprapubic and retropubic prostatectomy for prostatic hyperlasia.

The historical aspects, preoperative evaluation including preoperative note and postoperative flow sheet examples, and the surgical techniques of suprapubic and retropbuic prostatectomies are described in detail. These procedures allow relief from symptomatic prostatic hyperplasia with minimal morbidity and mortality.

Anesthesia, General↗