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Biomedical subjects

C Ursea

Publications and source records attributed to C Ursea.

33 records · Page 2Linked to original sources
PubMedDate not supplied

LAP negative and Ph1-positive hemorrhagic thrombocythemia.

Cytochemical and cytogenetic studies were carried out in 4 patients with chronic myeloproliferative disorders. These corresponded only partially to the clinical and hematologic criteria for the diagnosis of hemorrhagic thrombocythemia (HT), yet with a low leukocyte alkaline phosphatase (LAP) level and in the presence of the Ph1 positive 46, XX, mitoses. The authors discuss the significance of the presence of the Ph1 chromosome as well as the possibility of transition forms among chronic myeloproliferative disorders.

Adolescent↗
PubMedDate not supplied

Particular ultrastructural aspects in some splenectomized cases of hairy cell leukemia.

Some peculiar ultrastructural aspects of hairy cells obtained from the examination with SEM and TEM are presented. Images of erythrocyte rosette-formation around hairy cells in spleen as well as some additional data on the biogenesis of ribosome-lamellae complexes are reported. Some considerations on the origin of hairy cells are added.

Erythrocytes↗
PubMedDate not supplied

Congenital dyserythropoietic anemia type II. Radioautographic, ultrastructural and cytogenetical study in two familial cases.

The case of two sisters is reported in whom morphological (multinucleated erythroblasts in the bone marrow) and serological (positive Ham test, negative sucrose and water-sugar tests) characteristics of a congenital dyserythropoietic anemia type II were found. Radioautographic, cytogenetic and electron microscope studies confirmed the presence of an inefficient erythropoiesis and of a membrane defect, common in this disease. The finding of a nil LAP score has never been reported so far.

Adolescent↗