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Biomedical subjects

C Trichet

Publications and source records attributed to C Trichet.

9 recordsLinked to original sources
PubMed2002

[Care and management of cleft lip and palate by CLP Department hospital Robert Debre in Paris].

Cleft lip and palate repair must take a place at an early stage and respect physiology. Iatrogenic consequences harming maxillary growth must be avoided. Owing to early and reverse timing, short and long term results have been improved. Correction of the soft palate is performed at 3 months of age, lip and hard palate at 6 months without elevation of mucoperiosteum. A palatal plate is applied before and after each surgical stage. Patients receive phonetic, dental end ENT follow-up on a regular basis till end of growth. Correction of sequelae, especially of nasal tip, can be undertaken around grade school entrance at about 6 years of age. Nasal sequelae such as deviation of the septum must not be corrected before end of puberty. Surgery and follow-up must be conducted by an experienced multi-disciplinary team in which the surgeon plays the part of master of works.

Cleft Lip↗
PubMed1999

Multiple sclerosis associated with uveitis in two large clinic-based series.

The authors reviewed records from consecutive patients in an MS clinic (n = 1,098) and in a uveitis clinic (n = 1,530) to select patients with "definite MS" and uveitis. A total of 28 of 2,628 patients (1%) were identified: 12 from the MS clinic (12 of 1,098; 1.1%) and 16 from the uveitis clinic (16 of 1,530; 1%). Pars planitis and panuveitis were most commonly encountered. The delay between the onset of neurologic and ocular symptoms (mean, 9 years) emphasizes the importance of a sequential diagnostic search throughout the patient's course.

Adult↗
PubMed1993

[Treatment of herpetic endogenous uveitis with acyclovir by the systemic route].

Seventeen patients with presumed chronic herpetic uveitis of all anatomic types underwent systemic treatment with oral and/or intravenous, acyclovir. The diagnosis of herpes had been established on data from serological tests of the aqueous humor. Results were judged according to corticodependance and visual acuity. Results were all the more positive as treatment was more prolonged and also correlated with the dose of acyclovir injected intravenously or taken orally every day. Follow-up ranged from 6 months to several years.

Acyclovir↗
PubMed1993

[Viral uveitis].

The role of neurotropic virus in the etiopathogeny of uveitis is being emphasized by recent findings. Serology of aqueous humor is the first step towards the diagnosis since it indicates in many cases a local production of specific antibodies. Different entities seem to correspond to different viral specificities. The relationship between measles virus and multiple sclerosis may be one of the most fascinating aspects of this problem.

Eye Infections, Viral↗
PubMed1985

Scedosporium (Monosporium) apiospermum: multiple brain abscesses.

A 32-year-old female with alcoholic cirrhosis attempted to drown herself in a pond. She remained in a coma for 57 days. After a stormy course she developed multiple brain abscesses due to Scedosporium (Monosporium) apiospermum. Despite intravenous and intrathecal amphotericin B (total dose 870 mg) the patient died 71 days after the near drowning.

Adult↗
PubMedDate not supplied

Local production of IgG and IgG subclasses in the aqueous humor of patients with Fuchs heterochromic cyclitis, herpetic uveitis and toxoplasmic chorioretinitis.

Changes in local immunity are important when considering the physiopathology of uveitis. The aim of this study was to measure IgG and IgG subclass concentrations in the serum and the AH of patients with three different types of uveitis and to determine for each of them the presence of a local production of IgG in the intra-ocular compartment. This investigation was extended to IgG subclasses. Serum and AH of 46 patients, including 11 with Fuchs heterochromic cyclitis (FHC), 13 with toxoplasmic chorioretinitis, 11 with herpetic uveitis and 11 with senile cataract (taken as controls) were analyzed by ELISA for IgG and IgG subclasses. Three quotients (r1, IgG/albumin in serum; r2, IgG/albumin in AH; and R, r2/r1) were calculated in order to estimate the local synthesis (LS) of IgG and each IgG subclass. In AH of patients with herpetic uveitis, a concomitant and significant increase of all IgG subclasses as well as albumin (with no significant increase of r2 or R) was observed. This finding was interpreted as an indirect consequence of major damage to the blood-aqueous barrier. In patients with FHC, a significant increase of r2 and R involving only the IgG1 subclass was observed, indicating the existence of LS of IgG1 in the majority of these patients. In the AH of patients with toxoplasmic chorioretinitis, no significant modification of IgG subclass or albumin concentrations was observed when compared to controls. In conclusion, it would seem interesting to consider measurement of IgG and IgG subclasses and calculation of the coefficients r1, r2 and R for a better evaluation of the local immunological processes observed in different types of uveitis.

Adolescent↗