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Biomedical subjects

C Toussaint

Publications and source records attributed to C Toussaint.

212 records · Page 12Linked to original sources
PubMedDate not supplied

Electrophysiological effects of intravenous clonidine on sinus node function and conduction in man.

We studied the electrophysiological effects of clonidine in 10 patients (mean age, 69 years) without sinus dysfunction or atrioventricular block. An endocavitary study was performed with two multipolar catheters, one to record and stimulate the right atrium, the other to record the His bundle potential. The stimulations were delivered by an orthorhythmic stimulator. Clonidine, 150 micrograms, was injected intravenously over 10 min. The usual electrophysiological parameters for studying atrioventricular conduction and sinus function were measured under basal conditions, between the 10th and 25th min, and between the 25th and 40th min following the onset of the injection of clonidine. Sinus cycle length, maximum corrected sinus node recovery time, estimated atrio-sinoatrial conduction time, and premature atrial stimulation-response curve were not influenced by clonidine. There were also no changes in conduction interval, anterograde conduction point, effective refractory period of the atrioventricular node, and intraventricular conduction time. We conclude that intravenous clonidine does not change the electrophysiological parameters in man.

Aged↗
PubMedDate not supplied

[Minimal encephalitis in patients with renal transplant. Clinicopathological study and discussion of the role of the cytomegalovirus (author's transl)].

An autopsy was performed in ten patients recipients of renal allograft who died from cytomegalovirus pulmonary infection. In six patients, encephalitis lesions disseminated in the whole brain were observed. These lesions were not symptomatic. The particular features of this entity and its relationships with the type of immunosuppression therapy are discussed.

Brain↗
PubMedDate not supplied

Granuloma of the distal extremity of the ureter in kidney transplantation.

A granuloma of the distal extremity of the transplanted ureter was diagnosed in 8 of 180 patients operated on according to the Lich-Gregoir technique. This lesion was not observed in 116 patients with Politano-Leadbetter ureterovesical anastomosis nor in 61 patients with a ureterocystostomy constructed according to the technique of De Campos Freire et al. This complication seems to be specific of the Lich-Gregoir technique.

Granuloma↗
PubMedDate not supplied

[Acute renal insufficiency in surgery: the surgeon's role].

The surgeon has an active role to play in the treatment of acute renal failure (ARF) occurring in surgical patients. Surgical complications are very often the cause of ARF and their treatment is the only way to cure uremia.

Acute Kidney Injury↗
PubMedDate not supplied

Pyridoxine-responsive PH1: treatment.

Owing to the rarity of PH, the efficacy of pyridoxine therapy has only been tested in very small series of patients. From two recent reports including 18 patients, 50% of patients would be unresponsive to pyridoxine whereas oxaluria would be normalized in 20% of patients and somewhat reduced-but not to normal level-in the remaining 30%. In a few aneodotical cases pyridoxine administration was reported to improve kidney function in patients with renal failure secondary to hyperoxaluria. It is reminded that megadoses of pyridoxine (0.5 to 6 g daily) may induce severe sensory neuropathy.

Female↗
PubMedDate not supplied

[Long-acting neuroleptics. IV. Preliminary study of clopimozide (R 29764)].

Clopimozide is, in our opinion, a noteworthy neuroleptic drug. Its action is mainly ataraxic but also antidelusional, long-acting and accompanied with minimal side-effects. It is therefore particularly indicated in the maintenance therapy of psychotics, at a weekly dosage of 7.5 to 25 mg. The present conclusions are preliminary because of the limited number of patients (10) but also because of the rigidity of the trial protocol suggested to us.

Adjustment Disorders↗