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Biomedical subjects

C Torda

Publications and source records attributed to C Torda.

At least 37 records · Page 2Linked to original sources
PubMed1977

A glycoprotein fraction "modulator" of norepinephrine effects in vivo.

The effects of a fraction (Part A of Fraction 8) of a glycoprotein isolated by Lee on the physiological effects of norepinephrine have been studied by measuring the spontaneous activity of Purkinje cells of rats. Fraction A appears to be a "modulator" of norepinephrine because (1) it potentiated the effects of exogenous and endogenous norepinephrine by increasing the amplitude of the response, (2) it significantly prolonged those effects beyond average duration, (3) its effects disappeared only gradually, (4) in the concentrations tested (physiologically available concentrations and up to 20 times greater), it lacked neurotransmitter effects of its own. The effects of Fraction A on endogenous norepinephrine were concluded from (a) its effects on the intact Purkinje cell, (b) its effects on Purkinje cells deprived of norepinephrine content by 6-OH-dopamine or alpha-methyl-paratyrosine, and (c) its effects on Purkinje cell activities induced by stimulation with rectangular pulses of the afferent noradrenergic inhibitory neurons.

Action Potentials↗
PubMed1976

Bioelectric observations on adult and newborn hypothalamic dendrites.

Bioelectric activities of hypothalamic dendrites of newborn kittens and adult cats were recorded in vivo. Stimulation of various hypothalamic areas with electrical stimuli, or by injection of norepinephrine, generated propagated spikes in both newborn and adult neurons. The morphologically immature hypothalamic dendrites were hypersensitive to stimuli and were able to generate propagated spikes not only of axon hillock (adults) but also of dendritic membrane origin. Some mechanisms responsible for the two types of spike formation (newborn and adult) have been identified.

Animals↗
PubMed1976

Effects of catecholamines on behavior.

The potential for at least partial reversible transition of aggression- and anxiety-type symptomatology suggested searching for a potential biochemical link between subcellular mechanisms involved in the execution of aggression and anxiety. The effects of norepinephrine combined with dopamine and of epinephrine on these two types of behavior were tested. Responses to foot-shock were used to test aggression, extinction of avoidance response was used to test anxiety-type behavior. The results suggested that one of the possible links between the intracerebral processes responsible for execution of aggression- and anxiety-type behaviors is transmethylation of norepinephrine and/or dopamine to epinephrine.

Aggression↗
PubMed1976

Effects of recurrent postnatal stresses on hypothalamic concentrations of norepinephrine.

The effect of recurrent postnatal stress on the norepinephrine content of hypothalamus has been studied. Repeated exposure to hunger or to stimulation of the lateral nucleus of the hypothalamus served as stress-producing process. Regardless of their nature, recurrent stresses increased the norepinephrine content of the hypothalamus. The differences between controls and stressed animals were statistically significant.

Animals↗
PubMed1976

Effects of postinatal stress on visual and auditory evoked potentials.

Maturation of visual and auditory evoked potentials (mainly the P3 wave) of 10 controls and of 10 infants exposed to recurrent postnatal stressful events (crying spells lacking organic basis) have been compared. The sourse of maturation of P3 waves may serve as indicator of growth and nature of cognitive processes (including perception). Recurrent srying spells seemed to delay appearance of visual P3 wave, prolonged its latency, and delayed appearance of visible differences in the shape of visual P3 wave upon exposure of the subjects to different visual experiences. A compensatory increase of maturation of the auditory P3 wave appeared. The results suggest that recurrent exposure to stressful events during the early postnatal period may delay the ability of the memory banks of auditory engrams with unusual contents (including memory traces of stresses), a potential basis for future auditory hallucinations.

Acoustic Stimulation↗
PubMed1976

Why babies cry.

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Adult↗