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Biomedical subjects

C Tizian

Publications and source records attributed to C Tizian.

32 records · Page 2Linked to original sources
PubMed1984

[Joint saving forearm replantation using pedicled latissimus dorsi island flap].

In a case report, replantation of a subtotally amputated forearm at the elbow region is described. The elbow joint was reconstructed. At the end of the operation a huge soft tissue defect remained leaving the vein grafts unprotected. Using a latissimus dorsi myocutaneous island flap, the soft tissue defect was covered and the function of the biceps muscle restored.

Amputation, Traumatic↗
PubMed1983

Malignant degeneration in Madelung's disease (benign lipomatosis of the neck): case report.

Although not a common condition, benign lipomatosis of the neck (Madelung's disease) is well documented in the literature and to date we have failed to trace any reference to malignant change developing in this tissue. We wish therefore to report the case of a patient with benign lipomatosis of the neck in which malignant degeneration appeared after an interval of 6 years and in which this transformation from a benign to a malignant lesion was verified by histological examination.

Female↗
PubMed1983

[Problems with vascular end-to-end anastomoses].

Despite accurate preoperative investigation of the vessels of the lower part of the leg using angiography and plethysmography as a preparation for a free latissimus dorsi myocutaneous flap, problems can appear at the anastomosis during the operation. In the reported case using a free latissimus dorsi myocutaneous flap for coverage of a tissue defect at the lower leg, thrombosis appeared due to a difference between the calibers of the vein graft and the thoraco-dorsal artery. The existing difference of the calibers was therefore equalized by controlled narrowing of the vein graft. Thereby patency of the anastomosis was achieved and circulation in the free flap was guaranteed.

Adult↗
PubMed1983

[Continuous plexus anesthesia to improve circulation in peripheral microvascular interventions].

Five patients were demonstrated: one finger replantation, three toe-to-finger transfers and one finger-finger transfer. An axillary plexus catheter was inserted for postoperative sympathetic blockade. This brought about spasmolysis, an increase in the circulation and an increase in the acral systolic blood pressure. Simultaneously an adequate analgesic effect was achieved through the administration of local anaesthesic. The muscle relaxation assisted the immobilisation of the extremity. The improved circulation, the analgesic effect and the suppression of the muscular activity through continuous plexus anaesthesia have a beneficial influence on healing in replanted or transferred digits.

Adolescent↗
PubMed1983

[Restoration of an occipital cerebrospinal fluid fistula following roentgen injury].

After intensive radiation treatment following resection of a cerebellar tumor, necrosis of the occipital bone led to a chronic cerebrospinal fluid fistula. Because of eventual complications (constant loss of cerebrospinal fluid, meningitis, herniation of the brain) the chronic cerebrospinal fluid fistula needs to be treated as soon as possible. The treatment includes radical resection of the necrotic tissue, direct closure of the cerebrospinal leakage and stable soft tissue coverage. In the case presented closure was achieved with a free autologous fascia graft, cover with a myocutaneous trapezius island flap.

Cerebellar Neoplasms↗
PubMed1980

Using expanded polytetrafluoroethylene for bridging arterial microvascular defects: an experimental study with evaluation in the scanning electron microscopy.

In an experimental investigation the replacement of arterial microvessels with microporous expanded polytetrafluoroethylene was studied. The infrarenal segment of the rat aorta was used as the scientific model. The inside diameter of the micrograft was 1 mm. Using microvascular techniques a total of 18 prostheses were inserted. The animals were harvested at time intervals from 3 days up to 3 months. Patency was determined by angiography and at autopsy. The aorta implant junction, the characteristics of the neointima development and the differentiation of the interstitial cells were studied by scanning electron microscopy. Fourteen of the implanted micrografts remained patent at the time of sacrifice, yielding an early patency rate of 77,7%. As shown by scanning electron microscopy, the development of the neointima took place in 2 stages. The initial fibrin/platelet layer was reduced after one month and replaced by a definite neointima with mononuclear cells, connected with interstitial cells. Investigation of the aorta-implant junction showed the prosthesis functionally embedded in the structure of the aorta. Expanded polytetrafluoroethylene as a prosthetic material for microvascular prostheses was easy to handle and emerged compatible with other tissues. It can be used as a substitute for bridging arterial microvascular defects.

Animals↗
PubMed1980

[Modified histotechnical procedure for tissue evaluation of microvascular prostheses (author's transl)].

Porous silicone microvascular prostheses with a 1 mm inside diameter were inserted in the infrarenal part of the abdominal aorta of 35 rats. By modifying the usual histotechnical procedures like using paraffin with high consistence, embedding the specimen under vacuum and icing the sectional plane it was mde possible to produce perfect histological sections which guaranteed an exact histological evaluation of the implanted microvascular prostheses.

Animals↗
PubMed1980

[Thoracic wall reconstruction using autologous skin flaps and lyophilized dura: a comparative long-term study in dogs].

In an experimental study in dogs a defect in the chestwall was created by resecting two ribs on each side. The defect then was replaced by lyophilized dura and free dermis transplants. In X-ray observations and tissue examinations both materials are evaluated by comparing the results. After one year both graft materials showed identical results concerning function and tissue compatibility. Both, dura and dermis were totally resorbed replaced by collagen and connective tissue.

Animals↗