The present paper reports on the results of a haematologic and serologic survey carried out for assessing quantitatively and qualitatively the importation of malaria, in terms of the two routes of penetration of plasmodia in Moldavia. Examination of peripheral blood droplets and testing by indirect immunofluorescence showed the higher proportions recorded in subjects coming from endemic malarial areas (6.6% and 70.9% respectively) than in our citizens travelling abroad in malarial areas (0.1% and 3.3% respectively). Attention is drawn to the essential components of the epidemiologic situation today: the existence of a dynamic reservoir of import plasmodia that can only be partly detected and is added to the residual autochtonous reservoir of P. malariae, to the receptivity of the human population and the presence of the natural transmitter vector P. vivax.

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Rapid infusion of streptokinase standard dose in acute myocardial infarction is followed by a higher rate of coronary reperfusion than standard protocol.

There are several opinions asserting that the accelerated t-PA is more efficient than the standard protocol of streptokinase (SK) administration in acute myocardial infarction (AMI). One hundred patients admitted within the first 6 hrs after the onset of the symptoms revealing AMI were divided in two subgroups, as follows: subgroup A (50 patients) in whom a dose of 1.5 M.U. SK was infused in 20 min (accelerated protocol) and subgroup B (50 patients) in whom the same dose was infused in 60 min (standard protocol). In order to assess the efficiency of thrombolytic therapy (TT), we used three noninvasive criteria: the rapid resolution of the chest pain, the rapid decreasing of the ST segment elevation by more than 50% from the initial value, and the rapid increasing of enzymes revealing necrosis. Using the above-mentioned criteria, we considered that coronary reperfusion appeared in 40 patients from subgroup A (80%) and in 29 patients from subgroup B (58%). The speed of coronary reperfusion was 40 +/- 26 min in patients with accelerated SK and this time was significantly shorter than the time of 60 +/- 24 min registered in the control group. No major hemorrhagic events appeared in both subgroups. Although hypotension appeared more frequently in subgroup A, this minor complication was well supported by our patients. The rapid infusion of the standard dose of SK was followed by a higher rate and speed of coronary reperfusion as compared to the standard protocol.

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