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Biomedical subjects

C Stevens

Publications and source records attributed to C Stevens.

180 records · Page 10Linked to original sources

Responses to moral dilemmas in medical students and psychiatric residents.

There has been an increasing interest in the area of medical ethics as indicated not only by the recent proliferation of books and articles but also in the re-emergence of crucial moral issues such as euthanasia, abortion and the like. The difficulty with the existing literature is that these reports are often descriptive, anecdotal and situationally relative to the decision maker. In this study, the authors utilized a cognitive developmental approach to studying responses to moral situations not only because this approach is cross-culturally universal but also because it is not subject to situational variables. In this regard, the results of the assessment of medical students and psychiatric residents are presented as well as a comparison of moral reasoning stages in relation to the C.M.A. Code of Ethics. Recommendations for further research are presented.

Codes of Ethics↗

Consumer and provider attitudes toward dentist and expanded auxiliary functions.

Consumers, dentists, dental students, dental assistants, dental hygienists, dental assistant trainees, and dental hygiene students in Massachusetts were surveyed for their attitudes toward the concept of expanded-duties auxiliaries. The Osgood sematic differential technique was used, in which study participants were asked to respond to line drawings of a dentist or an auxiliary performing each of three different procedures: cutting tooth structure, placing a restoration, and taking radiographs. The results indicate that most of the groups perceived significant differences between cavity preparation by the dentist and by the auxiliary: they were modierately positive toward the former, near neutral toward the latter. Groups were more positive toward cavity restoration, generally perceiving fewer, but still significant, differences between the dentist and auxiliary as operatiors. All groups were most positive toward taking radiographs and perceived no difference between the two operators. Of all groups, the dentists perceived the greatest difference between operators; dental hygienists and dental hygiene students were the most positive and saw the least differences between operators. Consumers were the least positive to all procedures and perveived only modirate differences between the two operators. In other words, the consumers did not seem overly concerned with who provided the dental care; they just did not like the services themselves. In the study, the consumer was more concerned with the procedure than with the different operators, whereas the dentist was more concerned about the operator.

Attitude↗

Ammonia intoxication: a hazard during rehabilitation of protein-deprived rats.

The ammonia tolerance of weanling rats raised for 3 to 6 weeks on a protein-deficient diet was compared with that of a group of age-matched control animals raised from weaning on an optimal protein diet. The groups were challenged with a nitrogen load of either ammonium chloride or amino acids. The results of the loading studies indicate that severe protein deprivation increases vulnerability to ammonia poisoning. These observations suggest that ammonia-induced coma may pose a significant hazard during the initial intravenous rehabilitation of malnourished subjects, if replenishment is undertaken too vigorously.

Amino Acids↗

Lack of erythrocyte superoxide dismutase change during human senescence.

Superoxide dismutase (SOD), widely distributed in aerobic organisms, catalyzes dismutation of the superoxide free radical, O2-, to oxygen and hydrogen peroxide and apparently protects against oxygen toxicity. In human erythrocytes, O2- arises from autoxidation of oxyhemoglobin and SOD activity is copper-dependent. Since human erythrocyte copper content has been reported to decline in the fifth decade of life, we investigated the age dependence of human erythrocyte SOD activity. The mean SOD activity, assayed by inhibition of epinephrine autoxidation, was 415 +/- 66 units/g cells or 50 +/- 11 units/mg non-Hb protein. No significant difference was observed between young and old adults, and no correlations were detected with sex, state of health of the donor, or with blood hemoglobin content. The lack of general decline of SOD activity with age narrows the possible mechanisms for an involvement of O2- in senescence. SOD may yet decline in other longer-lived tissues or, as suggested by Fridovich, a constant low level of damage may be caused by imperfect scavenging of O2- by SOD. If such a mechanism is operative, it appears not to affect synthesis of SOD in erythrocyte precursor cells into the eighth decade of human life.

Aging↗