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Biomedical subjects

C Solassol

Publications and source records attributed to C Solassol.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Segment I of the liver or spigelian lobe. Anatomic study and surgical value].

Spigel's lobe, or segment I of the liver, currently represents the "smallest amount of hepatic parenchyma capable of regeneration". It is an autonomous lobe by virtue of its site and vasculo-biliary distribution, a true "accessory" liver connected to the "main" liver. Lesions of Spigel's lobe are rare, which is explained by the anatomy of the portal bifurcation. Hence the value of making every effort to preserve this segment during hepatectomy because of the possibilities of additional hepatic vein drainage. Segment I surgery is difficult and falls within the context of extended hepatectomies. Can Spigel's lobe be considered to be a "safety liver"? The possibility of subtotal hepatectomy, retaining only segment I, is being studied in the animal. It may be possible in man in the case of extensive hepatic lesions where only segment I is unaffected, as soon as effective artificial liver support is developed.

Animals↗
PubMed1982

[Contribution of artificial feeding to the prevention of fistulae, anastomotic breakdowns, and eviscerations. Applications to diffuse postoperative peritonitis in eight cases (author's transl)].

Based on the study of 8 cases diffuse post-operative peritonitis, the authors demonstrate in an exemplary manner the benefit derived through artificial nutritive support which permits, in certain well-defined cases, one-step digestive sutures and allows high-quality anastomotic and parietal healing. This new therapeutic attitude should not be generalized; it remains as yet very special, requiring specific metabolic safety measures. Only surgical teams in total control of the metabolic and nutritive problems accompanying heavy visceral surgery are in a position to apply this new concept.

Adult↗
PubMed1980

Complete nutrients mixtures with lipids for total parenteral nutrition in cancer patients.

Total parenteral nutrition with complete nutritive mixtures is a new adjunct therapy in cancer treatment, it must be the first and foremost type of nutritional support for many patients because it allows regional surgery in digestive cancer, abdominal radiotherapy without therapeutic interruption and sequential chemotherapy which is well tolerated. The patients may be maintained either on ambulatory or "home" parenteral nutrition.

Fat Emulsions, Intravenous↗
PubMed1980

[The hemostatic assistance after sub-total or total hepatectomy in the dog (author's transl)].

After subtotal (90%) or total hepatectomy in the dog, coagulation disturbances appear early and exclude survival beyond 40 hours. These disturbances are the result of a fall in the synthesis of coagulation factors, but may also reflect a consumption syndrome. The ensuing clinical finding is an intravascular coagulation which can give way to fibrinolysis. A substitutive therapy aiming to replace the missing factors and avoid or prevent an eventual consumption thus appears necessary. The hemostatic disturbances after subtotal or total hepatectomy in the dog can be totally corrected by a substitutive therapy based on fresh frozen plasma. The first hepatic segment (caudate lobe) cannot insure by itself the coagulation functions during the first 4 post-op days. The hemostatic assistance is an other step towards the treatment of hepatic insufficiency. It must become an integral part of existing artificial liver support.

Animals↗
PubMed1979

[Preoperative irradiation in the treatment of rectal carcinoma: study of results of 116 cases at five years (author's transl)].

Pilot study of combined radiosurgical treatment of carcinoma of the rectum. 116 patients underwent surgical excision of a carcinoma of the rectum after concentrated preoperative irradiation giving 40 grays in 18 sessions over the pelvic tumour volume. The operation in 79 cases consisted of abdomino-perineal excision and in 37 cases of anterior resection. The node involvement noticed on the resected volume is of 16,4 per cent. The operative mortality is of 7,7 per cent and the complications due to radiotherapy itself mainly a delay in cicatrisation. Survival rate at five years is of 60 per cent. Preoperative irradiation seems to be realy a benefit in the treatment of rectal carcinoma.

Adult↗
PubMed1978

[Artificial gastrointestinal tract in gastrointestinal neoplasms].

From 1970 to 1977 an artificial gut was used in 1350 patients suffering from gastrointestinal cancer. This type of prolonged intestinal assistance was recognized to be an important adjuvant in anticancer therapy with indications prior to, during and following the traditional course of treatment. Prolonged intestinal assistance makes it possible to reestablish or maintain a biological and clinical status in patients who must undergo aggressive anticancer therapy. The indications for its use are multiplying. In 54% of the cases parenteral nutrition is associated with therapy of the curative type and this percentage is continuously increasing.

Ambulatory Care↗
PubMed1978

[Parenteral nutrition and concentrated amino acid solution].

The authors report on their experience with a solution of amino acids concentrated at 25 gomegaN/liter in eighty patients on exclusive and total parenteral nutrition (TPN). The average duration of the TPN is 35.08 days. Azonutril 25 was given as nutritive melange, maintaining a calorie-nitrogen ratio of 150 to 200 calories for every added gram of nitrogen. The clinical and biological studies provide a series of arguments in favor of such an amino acid solution in total parental nutrition in patients with acute or chronic digestive insufficiency. No signs of renal or hepatic intolerance have appeared during this study. The improvement in nitrogen balance in fifteen patients is strongly significant (P less than 0.001) and can be correlated with weight gain and with the classic immunological tests.

Adolescent↗