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Biomedical subjects

C Sol

Publications and source records attributed to C Sol.

34 records · Page 2Linked to original sources
PubMed1979

[Value and limitations of sequential technetium 99m angiocardiography in the detection, localization and quantification of left-right intracardiac shunts apropos of 110 cases].

A comparative study of the diagnosis of intracardiac left-to-right shunts by isotope radiography on the one hand and oxymetry, abnormal catheter trajectory and angiocardiography on the other, was performed on a series of 110 patients, comprising 12 normals, 46 valvulopathies or cardiomyopathies without shunts, 23 ASDs, 22 VSDs, and 7 other shunts. Intravenous injection of Technetium 99 m with scintigraphic imagery and interpretation of time-activity curves detected even small left-to-right shunts and appeared to be more sensitive than oxumetry. The estimation of the size of the shunt correlated well with oxymetry for VSDs but not for ASDs. The localisation of the shunt was more difficult. The atrial level of the defect was detected in some but not the majority of cases. The isotopic technique appeared unreliable in the presence of severe haemodynamic disturbances. The isotopic method is a quick means of detecting left-to-right shunts without measurable risk, particularly useful in the investigation of children and young adults thought to have left-to-right shunts.

Adolescent↗
PubMed1978

[Assessment of the myocardial infarct size and kinetic study of the necrosis process by serial determinations of creatine kinase].

Assessment of the size of a myocardial infarct is important from a prognostic point of view, given the opportunities for surgical and pharmacological limitation of the process of necrosis. Serial doses of creatine kinase and its isoenzyme MB given every 4 hours for the first 48 hours of the infarct have allowed us to estimate the size of the infarct and to study the kinetics of enzyme liberation during necrosis. Unknown factors limit the sensitivity of this means of assessing the size of an infarct. The kinetic study showed that the enzyme is liberated by differing mechanisms.

Creatine Kinase↗
PubMed1977

[Myocardial scintigraphy after injection of thallium 201 during exercise test. Results in 74 patients].

Thallium 201 is rapidly fixed by the healthy myocardium and its radiation detectable by a scintillation camera. It may be used to reveal and localise ischaemic zones after intravenous injection. In 74 patients undergoing an exercise test, the results of so-called effort scintigraphy were compared with effort electrocardiograms, coronary arteriography and scintigraphy after the injection of Thallium 201 at rest (rest scintigraphy). The results of effort scintigraphy show a high degree of agreement with those of the effort electrocardiogram and of coronary arteriography. It would appear to be of great value in the determination of the permeability of aorto-coronary by-passes.

Coronary Artery Bypass↗
PubMed1977

[Scanning of the myocardium with pyrophosphate-technetium 99m. 367 cases].

Pyrophosphate-99m Tc injected intravenously is almost invariably fixed in the infarcted zone in transmural infarctions less than 8 days old. Fixation occurs in only 2/3 of cases of rudimentary infarction. The degree of fixation is more or less proportional to the size of the peak of creatine phosphokinase. After the 8th day following infarction, fixation is slight or nil. It is inconstant in pre-infarction syndrome or simple angina. This examination complements clinical, electrocardiographic and enzyme findings, in particular in the case of difficult diagnosis.

Angina Pectoris↗
PubMed1976

Myocardial scintigraphy with technetium 99m pyrophosphate.

The pyrophosphate of Tc99m attaches itself to ischaemic myocardial cells, and therefore makes it possible to obtain a scintigram of necrotic or necrosing myocardium. In a series of 65 cases the scintigram was positive in every case in which there had been a recent transmural infarct (17 cases). The results showed greater variation in the other ischaemic conditions involving the myocardium (limited infarcts or simple angina). The progress as a function of time was stuided in a series of fairly recent and older infarcts. The limitations and future prospects of this investigations are discussed.

Coronary Disease↗
PubMedDate not supplied

[Constrictive pericarditis and post-radiotherapy myocarditis with mitral incompetence (author's transl)].

The cardiac complications of radiotherapy of the thorax (e.g. for Hodgkin's disease and carcinoma of the breast) are various: 1) Pleural effusions, occurring a few months to two years after radiotherapy, spontaneously curable but may give signs of tamponnade or lead to constriction. 2) Constrictive pericarditis often several years after irradiation, with a poor prognosis in spite of attempts at pericardectomy which is indicated at the stage of hemodynamic constriction. 3) Myocardial involvement with advanced fibrosis and with various clinical presentations. The failure of pericardectomy and mitral incompetence were evidence of myocarditis in the case reported here.

Adolescent↗