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Biomedical subjects

C Senent

Publications and source records attributed to C Senent.

At least 19 recordsLinked to original sources

Safety and efficacy of argon plasma coagulator ablation therapy for flat colorectal adenomas.

INTRODUCTION: argon-plasma coagulation (APC) has been used safely and efficaciously in multiple settings including colon polyp treatment. The aim of this study was to evaluate APC efficacy and safety in the treatment of flat colorectal adenomas. MATERIALS AND METHODS: APC ablation was prospectively performed and evaluated in 22 consecutive patients with colorectal adenomas, 11 of which had large sessile adenomas that were treated with piecemeal polypectomy and APC ablation of residual adenomatous tissue, whereas the remaining eleven patients with flat or carpet-like adenomas were only treated with APC. The mean initial longitudinal extension of adenomas to be treated with APC was 22 mm (range, 20 to 40 mm). RESULTS: the mean age of patients was 70 years. Adenomas were found most frequently in the rectum (50%) and cecum (23%). Complete ablation was achieved in 90.9% of adenomas. Recurrence was observed in 20% of patients, all of them in the rectum, after a mean follow-up period of 16.3 months (range, 8 to 35). All recurrences were managed satisfactorily. No major complications were seen. CONCLUSIONS: argon plasma coagulator ablation of flat colorectal adenomas is an efficacious and safe technique, specially in the right colon, but results must be confirmed in controlled trials with a higher number of patients.

Adenoma↗

[Mucin-hypersecretory pancreatic tumors: a pathology with defined characteristics].

We report a case of a mucin-producing tumor of the pancreas, a rare neoplasm of which only a few cases have been described in Europe. The finding of progressive hyperamylasemia without abdominal pain suggests the presence of this type of tumor. At endoscopic retrograde cholangio-pancreatography (ERCP), mucinous excretion and ductal dilation were found. Its prognosis is better than adenocarcinoma.

Adenocarcinoma, Mucinous↗

[Idiopathic esophageal ulcer with fistulization to the bronchial tree in a HIV-positive patient].

Idiopathic esophageal ulcerations (IEUs) associated with human immunodeficiency virus (HIV) infection are now recognized as an important cause of esophageal disease in this population. We report one case of IEU complicated with a fistula to the bronchial tree. Given his variable appearance, which may mimic other causes of esophageal ulceration and the high response rate to oral corticosteroid therapy, all HIV infected patients with esophageal ulceration should undergo endoscopy with biopsy to obtain a definitive diagnosis. We review the literature about the etiology, pathogenesis, management and treatment of the IEU.

Bronchial Fistula↗

[Tracheoesophageal fistula secondary to endoscopic sclerotherapy of esophageal varices].

Over the past 15 years, endoscopic variceal sclerotherapy (EVS) has become the main therapy for patients with bleeding esophageal varices. EVS has the advantage of a low associated mortality and morbidity, but may lead to serious complications. We report a case of esophagotracheal fistula complicating sclerotherapy that resolved with nonsurgical management.

Aged↗

[Hydrogen peroxide-induced lesions in the digestive tract. Apropos 4 cases].

Gastrointestinal injury caused by caustic products a are relatively infrequent, occurring mainly in the upper gastrointestinal tract. Accidental ingestion accounts for most of the cases, and the severity and extent of damage produced, depends on the composition and volume of the caustic agent ingested; endoscopy is a safe and effective diagnostic procedure. We report four unusual cases of caustic injury of the gastrointestinal tract due to hydrogen peroxide, two cases due to oral ingestion and another two due to the accidental administration of enemas, there was a good clinic and endoscopic recovery with conservative treatment.

Accidents, Occupational↗

[Hypertensive colopathy: its endoscopic evaluation and evolution following a liver transplant].

In the last decade the association between intestinal vasculopathy and Portal Hypertension (PH) has been established on the basis of endoscopic, histological and histomorphometric examinations. We report the case of a patient with cirrhosis secondary to hepatitis C virus, in whom colonoscopy demonstrated the presence of colonic vascular lesions with cherry spots appearance in the rectum and left colon that vanished two weeks after liver transplantation. The disappearance of mucosal lesions after liver grafting suggest a relation ship among them and portal hypertension.

Colonic Diseases↗

[Elastic band ligation: preliminary experience in esophagogastric varices].

Endoscopic ligation is a new technique that shows an efficacy for acute hemorrhage and prevention similar to sclerotherapy. Its principal advantage is the smaller number of complications (2%), which seem to be related to the presence of post-treatment ulcers which are indeed more extensive but more superficial. In our preliminary study on 8 patients, eradication of varices in 62.5% was obtained. The mean number of bands placed at each ligation session was of 2.4 +/- 0.96 and the mean number of treatment sessions to achieve the eradication was 3.4 +/- 1.5. The complications that appear during the positioning of bands, a minimum bleeding was observed during the polyp formation, and in one occasion, the partial detachment of an eschar followed the bleeding was also observed. Rebleeding occurred in two patients (25%), and in other patient, spontaneous bacterial peritonitis was observed. The two patients who presented recurrent variceal bleeding, received a transjugular intrahepatic portosystemic shunt to control their hemorrhage.

Adult↗

Fixed drug eruption caused by sulfaguanidine.

We report a patient who developed a fixed drug eruption (FDE) due to sulfaguanidine. This drug has not been previously implicated as a cause of FDE. The diagnosis was confirmed by an oral provocation and a biopsy of the lesion. Oral provocations with other sulfonamides, sulfamethoxazole and sulfadiazine, were well tolerated.

Administration, Oral↗

[Angiodysplasia of the colon. Experience in 60 cases].

A review was made of 60 angiodysplasias of the colon (AD) found retrospectively among 2,750 colonoscopies. The most frequent clinical manifestation was rectal bleeding (65%); mean patient age was 63 years. More than a fourth of the angiodysplasias (26.6%) was located in the left colon, as compared to 66.6% in the cecum and ascending colon. Most of the lesions were multiple and less than 5 mm in diameter. Twenty-two percent of the patients were cirrhotics and 15% had an aortic valvular lesion. The most outstanding aspects of the process are reviewed.

Adolescent↗

[Colonoscopic approach in the therapy of sigmoid volvulus].

We present 13 patients with 15 episodes of colonic volvulus, who underwent colonoscopy to decompress and/or devolvulate. Colonoscopic exploration demonstrated a non obstructive dilatation in three cases. In the remaining 10 patients, with 12 episodes of volvulus, decompression was obtained in 83.3% and devoluvulation in 41.6%. There were two failures, due to peritoneal metastases and adhesions which fixed the volvulus. In 40% of the cases there were mild ischemic signs. Forty per cent of the patients were submitted to elective surgery and the two failures (20%) were operated in emergency. The remaining 4 patients declined surgical treatment. At is allows differential diagnosis, we think that, for these patients, colonoscopy should be the first therapeutic approach; it also allows decompression and/or devolvulation and an early diagnosis of the associated ischemia.

Adult↗

[Role of endoscopy in caustic gastroesophageal lesions].

From 1984 to 1989 we have examined endoscopically 191 patients who ingested, for different causes, some type of caustic substance. The mean age was 36.8 +/- 21 years. 57% were female and 43% males. The most common substance was lye (52%). The clinical symptoms consisted mainly of epigastric pain and odynophagia. The most prevalent lesion was oesophagitis, of variable degrees (58%). Complications related to the ingestion of the caustic appeared in 20% of the patients; three of them died. The most common sequela was oesophageal stenosis and secondly gastric stenosis. Males ingested acids more frequently than females (P less than 0.001). In 20% of the cases the ingestion of the caustic was for suicide while in children all the cases were accidents.

Accidents↗