Biomedical subjects
C Scully
Publications and source records attributed to C Scully.
Gastroenterological diseases and the mouth.
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Recurrent herpes labialis: efficacy of topical therapy with penciclovir compared with acyclovir (aciclovir).
This study compares the effects of topical acyclovir and penciclovir in the treatment of recurrent herpes labialis. The study patients were a population of 40 patients with in excess of five recurrences annually, and were separated into four homogeneous groups each of 10 subjects. The antiviral creams were used to achieve total lesional cover, every 2 h during waking hours. The effects on the time to lesion crusting and to resolution of pain, were assessed. The results not only confirmed that aciclovir is ineffective, but confirmed that penciclovir is effective, and that penciclovir is superior to aciclovir.
The mouth in heart disease.
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Orofacial effects of antiretroviral therapies.
This paper summarises some of the oral adverse effects of antiretroviral agents. Some are related to bone marrow suppression which may also predispose to mouth ulcers. Erythema multiforme and toxic epidermal necrolysis are especially well recognized in HIV disease, particularly as reactions to sulphonamides and to antiretroviral agents. Oral lichenoid reactions have been described in HIV disease often relating to zidovudine use. Didanosine has also produced erythema multiforme and not unusually induces xerostomia, again by an unknown mechanism. Xerostomia may be seen in up to one-third of patients taking didanosine. Taste abnormalities are common with the protease inhibitors and oral and perioral paraesthesia can be a disturbing adverse effect. Ritonavir in particular can give rise to circumoral paraesthesia in over 25% of patients. Indinavir can also produce cheilitis.
The role of saliva in oral health problems.
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The mouth in dermatological disorders.
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Genoprevalence of TT virus among clinical and auxiliary UK dental healthcare workers: a pilot study.
BACKGROUND: In 1997 a new human hepatotropic virus, TT virus (TTV), was identified. The clinical significance of TT virus infection remains unclear. OBJECTIVE: To undertake an initial evaluation of the genoprevalence of TTV DNA among health care workers in the United Kingdom. SETTING: A UK dental hospital. STUDY DESIGN: The sera of 53 dental healthcare workers (9 dentists, 14 dental nurses and 30 office staff) were tested for the presence of TTV DNA using Polymerase Chain Reaction (PCR). RESULTS: TT virus DNA was detected in 3 out of 53 (5.7%) samples. This frequency of TTV carriage is similar to that of blood donors and healthy persons in the UK. CONCLUSION: The present data suggest that dental healthcare workers in the UK are not at increased risk of nosocomial acquisition of TT virus.
Changing procedures.
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Special needs dentistry.
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ABC of oral health. Dental emergencies.
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ABC of oral health. Improving occlusion and orofacial aesthetics: tooth repair and replacement.
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ABC or oral health. Improving occlusion and orofacial aesthetics: orthodontics.
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ABC of oral health. Swellings and red, white, and pigmented lesions.
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ABC of oral health. Mouth ulcers and other causes of orofacial soreness and pain.
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ABC of oral health. Oral cancer.
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ABC of oral health: periodontal disease.
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ABC of oral health. Dental damage, sequelae, and prevention.
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