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Biomedical subjects

C Schrader

Publications and source records attributed to C Schrader.

34 records · Page 2Linked to original sources
PubMed1998

Evaluating the sizes of Lightspeed instruments.

The diameters of six different sized Lightspeed cutting heads were measured using a modified optical micrometer. Six specimens of instrument sizes 20, 22.5, 27.7, 30, 32.5 and 45 were examined. Except for one cutting head of size 30, all the recorded diameters were oversized compared to the expected diameter and the permitted tolerance (+/- 0.005 mm). Perfectly machined instruments would increase by 12.5%, 9.09% and 8.3% from instrument sizes 20-22.5, 27.5-30 and 30-32.5, respectively. Under the conditions of this study, the corresponding increases were 7.1%, 6.75% and 8.54%. Instrument size 20 had the widest range and is the smallest instrument in the Lightspeed set. The largest differences between the recorded and expected means were registered for the size 45 group. An earlier study using a different measuring method reported that Lightspeed instruments were mostly undersized.

Dental Instruments↗
PubMed1997

Viral zoonosis from the viewpoint of their epidemiological surveillance: tick-borne encephalitis as a model.

Tick-borne encephalitis (TBE) is a vector borne and, more rarely, a food (milk, milk products) borne disease of humans. For further characterization of the virus activity in natural foci of TBE more than 32,000 unengorged wild ticks were caught in low and high virus active foci in Germany (Mecklenburg-Western Pomerania, Saxony, Brandenburg, Thuringia, Bavaria, Baden-Württemberg, Saarland). The ticks were examined by RT-PCR and Southern blot hybridization as well as by classical virological methods. The dynamics of such natural foci of TBE in the last 35 years were discussed. Also nucleotide sequence data of parts of the virus genome (5'-non coding region) of 16 European and some Far East subtype strains were compared.

Animals↗
PubMed1992

Analysis of internal proteins of influenza A (H2N2) viruses isolated from birds in East Germany in 1983.

Proteins and RNAs of influenza A (H2N2) viruses isolated from birds in 1983 in East Germany were compared antigenically with those of H2N2 human strains. The electrophoretic mobility of the viral proteins and of the S1-treated double-stranded RNAs from two human and six avian strains, as well as the results of EIA-tests using monoclonal antibodies to their matrix protein and nucleoproteins indicate an antigenic relationship between the avian isolates and human strains of H2N2 subtype. One of the avian strains had a reduced amount of matrix protein.

Animals↗
PubMed1991

Blood mononuclear cells from patients with severe congenital neutropenia are capable of producing granulocyte colony-stimulating factor.

Severe congenital neutropenia (SCN) is a disorder of myelopoiesis characterized by severe neutropenia or absence of blood neutrophils secondary to a maturational arrest at the level of promyelocytes. We examined peripheral blood mononuclear cells (PBMC) of SCN patients who demonstrated normalization of their blood neutrophil counts in a phase II clinical study with recombinant human granulocyte colony-stimulating factor (rhG-CSF). When stimulated in vitro with bacterial lipopolysaccharides (LPS), PBMC of those SCN patients produced G-CSF activity, as judged by proliferation induction of the murine leukemia cell line, NFS-60. Western and Northern blot analysis showed G-CSF protein and G-CSF-mRNA indistinguishable in size from those of normal controls. We conclude that PBMC of the SCN patients tested are capable of synthesizing and secreting biologically active G-CSF in vitro.

Adult↗
PubMed1988

[Case report of Fox-Fordyce disease].

A rare case of Morbus Fox-Fordyce in a patient under the hormonal contraceptive pill Trisiston has been reported. Morbus Fox-Fordyce was diagnosed by histological examination after exclusion of other diseases. Six months after beginning of treatment using Norethisterone patient is well.

Adult↗
PubMed1986

Studies of some biological and molecular characteristics of avian influenza A/H7 (Hav1) subtypes.

Current isolates of the subtypes H7N3 and H7N7 from 1979 to 1981 were examined and compared with the reference strains with regard to their antigenic variability and to their pathogenicity for birds and mammals in order to establish the potentiality of influenza A/H7 virus (Hav1) transmission from birds to mammals. The analysis of the electrophoretic mobility of virus-induced polypeptides and of the double-stranded RNA segments after hybridization revealed equal, similar and deviating patterns. A substantial drift was determined in the surface antigens, especially in the neuraminidase. The avian strains replicated also in mammalian cells and were pathogenic for mammals. All strains examined were reisolated from the infected mammals; they caused more pronounced inflammatory changes in the trachea and lungs of infected mammals than in those of birds.

Animals↗
PubMed1979

A behaviorally-oriented activities therapy for program for adolescents.

A behaviorally-oriented activities therapy program was designed and implemented with adolescents who manifested problems in school, at home, and with peers. Baseline measures for target behaviors were taken within the activities therapy program and, after a behavioral analysis, specific techniques were chosen to remediate problems. Techniques employed included: contingency contracting, assertiveness training, relaxation training, and cognitive restructuring. Evaluation of the effectiveness of each program was performed through daily measurement of the frequency of the occurrence of the target behaviors. Three case studies are presented which are illustrative of the range of programs which can be successfully implemented with this population.

Acting Out↗