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Biomedical subjects

C Sbokos

Publications and source records attributed to C Sbokos.

7 recordsLinked to original sources
PubMed1980

Primary malignant mediastinal germ cell tumors: a study of three cases.

Three patients with primary malignant mediastinal germ cell tumors are presented and the literature is briefly reviewed. A great disparity exists in the literature regarding the classification and differential diagnosis of these tumors. Resection and irradiation of seminomas give relatively satisfactory results. The prognosis of malignant teratomas, embryonal cell carcinomas and choriocarcinomas is poor, regardless of the mode of treatment.

Adult↗
PubMed1980

The influence of prearrest factors on the preservation of left ventricular function during cardiopulmonary bypass.

Uniformly excellent myocardial protection during global ischemia in cardiac procedures requiring cessation of aortic root perfusion remains an elusive goal. This study establishes the importance of the preischemic inotropic state of the left ventricle and the arterial blood glucose concentration ([glucose]) immediately prior to an elective period of myocardial ischemia. Thirty-one experiments were performed on dogs subjected to 90 minutes of global ischemia on cardiopulmonary bypass at 28 degrees C with perfusion pressure constantly maintained at 90 mm Hg. The maximum rate of development of left ventricular pressure (LVdp/dtmax) at constant arterial and left atrial (LAP) pressures was used as a measure of contractility prior to ischemia. In a group of 18 of these dogs undergoing anoxic cardiac arrest, arterial blood [glucose], in conjunction with the preischemic LVdp/dtmax and the cross-clamp to asystole time interval (metabolic supply/demand index), significantly predicted (p less than 0.01) the functional result following the standard ischemic insult. In 13 other dogs with [glucose] greater than 120 mg/100 ml and treated with potassium cardioplegia, "normal" preischemic LVdp/dtmas (N = 7) was associated with a good functional result, but an elevated preischemic LVdp/dtmax (N = 6) produced severe functional impairment following ischemia. Optimum myocardial protection thus involves minimizing metabolic demands and maximizing metabolic supply immediately prior to and during the period of aortic cross-clamping.

Animals↗
PubMed1976

The use of bronchoscopic sponge biopsy in the diagnosis of pulmonary neoplasms.

A modified method of transbronchoscopic sponge biopsy is presented a series of 212 patients is discussed. A diagnostic accuracy rate of 89 per cent was obtained in the 159 cases of proved carcinoma. False-positive and false-negative results are discussed. This technique was found to be an easy, rapid, accurate, and inexpensive method of obtaining samples for cytologic evaluation in the preoperative work-up of patients with suspected pulmonary malignancies.

Adenocarcinoma↗