Human mammary carcinoma cell line: infection by an avian myxovirus as a prerequisite for immunopotentiation.
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Animals↗
Biomedical subjects
C Sauter
Publications and source records attributed to C Sauter.
Fowl plague virus adapted to human leukemia cells: interaction with normal human leukocytes and plastic surfaces.
An avian influenza A virus which grows well in human leukemic myeloblasts was unable to replicate in normal human leukocytes. The virus adhered during the first hours of incubation to plastic surfaces and to leukocytes and was then released into the supernatant; care should be taken not to confuse this with viral growth.
Adaptation, Physiological↗
Replication of an avian myxovirus in tumor cell cultures obtained from effusions of mammary carcinoma patients.
In view of the possible use of viruses for the immunotherapy of breast cancer, the replication of a strain of fowl plaque virus was studied in the tumor cells of 11 mammary carcinoma patients with malignant effusions. The tumor cells were obtained by centrifugation on iodamide solutions, then cultured in vitro, and infected by a fowl plaque virus previously adapted to grow in a mammary carcinoma cell line. Virus multiplication was observed in all cases, a prerequisite for the use of autologous viral oncolysates for immunotherapy in mammary carcinoma patients.
Ascitic Fluid↗
[Replication of an animal myxovirus in primary cultures of human leukemic cells: condition for immunotherapy of acute leukemias with virus oncolysates. Preliminary report].
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Animals↗
[Internistic management of malignant lymphoma].
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Antigens, Neoplasm↗
Fowl plague virus adapted to human epithelial tumor cells and human myeloblasts in vitro. II. Replication in human leukemic myoloblast cultures.
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Adult↗
Fowl plague virus adapted to human epithelial tumor cells and human myeloblasts in vitro. I. Characteristics and replication in monolayer cultures.
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Animals↗
Replication of an avian myxovirus in primary cultures of human leukemic cells.
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Cells, Cultured↗
[Therapy of generalized Hodgkin's disease. Results of cooperative studies (1967-1972)].
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Antineoplastic Agents↗
[Acute myelogenous leukemia: trial therapy with a myxovirus adapted to myeloblasts].
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Age Factors↗
Agglutination of leukemic myeloblasts by neuraminidase.
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Cell Aggregation↗
[Diagnostic significance of cell cultures from pleural effusions and ascites].
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Ascitic Fluid↗
Rosette formation in white blood cell cultures from patients with acute myeloblastic leukemia.
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Culture Techniques↗
[Fundamental principles of cytostatic combination therapy].
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Antineoplastic Agents↗
Interferon-like inhibitor and lysosomal enzyme induced in mice injected with endotoxin.
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Animals↗
Doxorubicin adjuvant combinations for breast cancer.
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Antineoplastic Combined Chemotherapy Protocols↗
Influence of a new relapse treatment for acute myeloid leukemia (AML) on in vitro granulopoiesis.
Twelve AML patients in relapse were treated with cytosine arabinoside (Ara-C), VP 16-213, vincristine, and vinblastine (A-triple-V). For bone marrow (BM) evaluation, in vitro granulopoiesis by agar and liquid cultures was investigated. In 15 treatments, 12 complete remissions (CR) were observed. Three patients, treated with 2 A-triple-V cycles achieved CR twice. One to four months after treatment normal colony formation and cell differentiation was found in remission patients. Evidence of sustained recovery was obtained in sequential studies of BM cultures of patients in CR. These results indicate that-A-triple-V treatment does not irreversibly deplete normal myeloid progenitor cell population.
Adult↗