Search PubMed⌕ Search

Biomedical subjects

C Sainte-Rose

Publications and source records attributed to C Sainte-Rose.

85 records · Page 5Linked to original sources
PubMed1982

[Cerebral abscesses in children treated by puncture. A 16 year-experience].

In the last 16 years, 33 children have been treated for brain abscesses. Fifteen (45.5%) presented with cyanogenic congenital heart disease; eleven (33.5%) with E.N.T. infection. The standardized treatment protocol included puncture of the abscess, antibiotherapy and anti-edematous drugs. Postoperative permanent epidural ICP monitoring and, in the last 6 years, repeated CT scans indicated when it was necessary to tap the abscess again or to reinforce the anti-edematous treatment. However, in 3 of these 33 cases, the abscess had to be removed. Postoperative mortality rate was 3%. Overall mortality rate was 6%. Neurological sequelae were slight. Epilepsy occurred in 10%. Mental retardation (16%) was only found in children with cyanogenic congenital heart diseases. Repeated CT scans showed the progressive disappearance, within a few months, of the abscess membranes. This study shows an improvement in the results when brain abscesses in children are punctured rather than excised.

Brain Abscess↗
PubMed1982

[Congenital intraspinal neuroblastomas. A propos of 7 cases treated surgically].

Neuroblastomas appear to be one of the most frequent congenital solid tumors. Nevertheless, intraspinal congenital neuroblastomas are uncommon. The authors report seven cases of congenital intraspinal neuroblastomas operated on in the "Service de Neurochirurgie des Enfants-Malades" from 1970 to 1980. Their study and that of 16 cases published in the literature allows to stress several points (7, 12). The dumb-bell intraspinal neuroblastomas present a large extension. They usually determine a severe and definitive paraplegia. They probably have a long prenatal evolution. The tumoral prognosis of these congenital neuroblastomas is good. Success should be expected in nearly 80% of the cases. Surgery, in two steps, intra and extra spinal, remains compulsory even though the neurological prognosis is poor. It is useless to operate upon the neuroblastomas as emergencies, when neurological involvement is total at birth. The complementary treatment, X ray-therapy or chemotherapy is not without any danger on newborns. It necessary is not proved.

Female↗
PubMedDate not supplied

Mechanical complications in shunts.

A retrospective study was conducted on 1,719 hydrocephalic patients, treated between 1974 and 1983 at the Hospital for Sick Children (Toronto) and l'Hôpital des Enfants Malades (Paris), in order to better understand shunt failure. The statistical analysis demonstrates the following: (1) A probability of occurrence of shunt malfunction of 81% at 12 years of follow-up. (2) A high prevalence of shunt obstruction (56.1% of all malfunction) and fracture or disconnection of the tubings (13.6%). (3) A higher risk of proximal occlusion with flanged ventricular catheter. (4) Less malfunction with proximal-non-slit valves as compared to distal-slit valves. (5) The importance of pressure-flow characteristics of the shunt; because of an indirect relation between overdrainage and proximal occlusion. (6) A correlation between connectors and migration or fracture of the shunt. (7) Less distal obstructions when an open-ended distal-catheter was used. These complications were of some clinical, psychological and economical consequences. Their rate could be lowed.

Cerebrospinal Fluid Shunts↗
PubMedDate not supplied

Shunt obstruction: a preventable complication?

Mechanical shunt complications account for more than half of all shunt failures. This study compares the incidence and etiology of mechanical shunt failure in a recent series of 343 pediatric patients with a flow-regulating shunt, Cordis Orbis-Sigma valve (OSV; Cordis, Miami, Fla., USA) to a previous series of 1,719 pediatric patients with standard differential pressure (DP) valves. The 1- and 5-year shunt failure probabilities were 20.1 and 23.6%, respectively, for the OSV valve and 31.1 and 49%, respectively, for the standard DP valves. The incidence of slit ventricles was 8.2% for the OSV and 33.2% for the conventional DP valve. Proximal obstruction remained the commonest cause of failure in both groups. Valve obstruction was higher (18.3 vs. 9.7%) with the OSV, although the obstructions tended to occur mostly in the early postoperative period possibly for debris introduced at the time of insertion. This review of the mechanical complications reported in this and other series suggests that despite the complexity of the interactions between variables associated with the patient, the surgeon and the shunt, mechanical complications are to a significant degree preventable. Verification will require prospective randomized clinical trials.

Brain↗
PubMedDate not supplied

[True precocious puberty in non-tumor hydrocephalus. An analysis of 16 cases].

True precocious puberty occurred in 16 children (15 girls and 1 boy) with non tumoral shunted hydrocephalus at a mean age of 6.8 years. They had mild clinical manifestations of precocious puberty, and the other pituitary functions were found to be normal. Except for one child, precocious puberty did not correlate with raised intracranial pressure or lack of cerebral drainage by the shunt. Growth was the main concern in this group as the predicted height fell at a mean value of 1.7 SD below the parental target height, and even more in children with myelomeningocele. This growth retardation is due to an early progression of bone age observed even prior to the appearance of breast or pubic hair. Therefore we suggest that these children might benefit from early treatment by an LHRH analogue as soon as precocious puberty occurs.

Age Factors↗
PubMedDate not supplied

[Vertebral eosinophilic granuloma and spinal cord compression].

We describe a case of spinal eosinophilic granuloma inducing a medullary compression syndrome. However, this condition appears to be very infrequent, since only 16 cases were reported in literature. The difficulties of the diagnosis of this disease and its therapeutic management are discussed.

Eosinophilic Granuloma↗