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Biomedical subjects

C S Williams

Publications and source records attributed to C S Williams.

At least 145 records · Page 8Linked to original sources
PubMed1978

Psoroptic ear mites in dairy goats.

Of 24 adult dairy goats examined at necropsy, 21 were found to be infected with ear mites (Psoroptes cuniculi), but none had gross signs of ear scab. Clinical examination of approximately 200 live adult goats on 23 farms revealed ear scabs in only one animal; however, the frequency of head shaking and ear scratching was high. On one farm with 170 lactating does, most of 25 kids examined within 6 weeks of birth were found to be infested. Serial examination of growing kids on another farm revealed mites in the ears of kids by 10 days of age. The onset of clinical signs of ear mite infestation was evident in all kids on the property during the 3rd week of life. In one instance when infested adult goats and kids were penned with adult sheep and lambs, there was no evidence of cross infestation.

Animals↗
PubMed1978

Fetal blood velocity waveforms.

In this paper a method is described for obtaining and characterizing fetal blood velocity waveforms. The signals were recorded with a range-gated Doppler instrument and characterized after spectral analysis. Preliminary observations indicate differences in the waveforms obtained during normal pregnancies compared with some complicated pregnancies.

Blood Flow Velocity↗
PubMed1977

Evaluation of a polycarbonate filter for the detection of microfilaremia in dogs in central Michigan.

Several diagnostic techniques were used in determining the prevalence of microfilaremia in 479 dogs entering the holding facility for research animals at Michigan State University. The modified Knott test and cellulose filter procedures were initially applied, but persistent difficulties with the cellulose filter system prompted evaluation of the use of clear polycarbonate filters. This procedure was found to be equally as sensitive as the modified Knott test and more sensitive than the microhematocrit tube method. Microfilariae trapped on polycarbonate filters were easy to detect, and there were no problems with clogging of the filter pores. Losses of up to 3.5% of the microfilariae occurred with 8-micron pore size filters, but no more than 1% passed through 5-micron pore size filters. Identification of microfilariae was based on size and shape of the parasites. In questionable cases, the diagnosis was confirmed by means of the histochemical test for acid phosphatase distribution. Satisfactory results were obtained when the latter test was applied to microfilariae of Dirofilaria immitis trapped and fixed on filters. Twenty blood samples in the surgery (4.2%) contained microfilariae, all of which were classified as D imitis.

Animals↗
PubMed1975

An epizootic of cerebral nematodiasis in rabbits due to Ascaris columnarus.

An epizootic of cerebral nematodiasis due to ascaris columnaris occurred in a commercial rabbitry, and 80 diseased rabbits died or were killed. The morbidity was high in groups of recently purchased rabbits and in the offspring of 12 breeder rabbits. The breeder rabbits which had been on the farm for more than a yr survived the outbreaks. Wild animals and birds had access to the facilities, but raccoons and skunks were never observed. A columnaris larvae were found on histopathologic examination. and live larvae were recovered from brains of 2 diseased rabbits.

Animals↗
PubMed1975

The immunological response of the rat to infection with taeniaeformis. IV. Immunoglobulins involved in passive transfer of resistance from mother to offspring.

Weanling rats born of mothers infected with Taenia taeniaeformis were found to be passively protected against homologous challenge. Cross-fostering of normal suckling rats onto immune mothers established that passive transfer occurred via the colostrum and milk. Immunoglobulin fractions containing gammaA from immune colostrum were fed to 12-14-day-old rats for 4 days via stomach tube. Significant passive protection against challenge with T. taeniaeformis was achieved with gammaA from one of three colostrum pools. The effect of colostral gammaA preparations on the infectivity of freshly hatched oncopheres of T. taeniaeformis was measured by the intra-intestinal inoculation of immunoglobulin solutions into isolated gut loops containing hatched eggs of the parasite. gammaA from one of three pools of immune colostrum caused a significant reduction in the number of parasites which reached the liver. This appears to be the first time that protective activity against a helminth infection has been achieved with gammaA. A fraction of immune colostrum containing both 7Sgamma1 and 7Sgamma2 immunoglobulins was found to confer passive protection when inoculated parenterally. In view of the prolonged period of absorption (ca 18 days) of 7S immunoglobulins from the gut by the suckling rat, it seems likely that these antibodies are primarily responsible for the natural passive transfer of protection from mother to young.

Aging↗