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Biomedical subjects

C S Soo

Publications and source records attributed to C S Soo.

At least 37 records · Page 2Linked to original sources
PubMed1983

The fatty liver: pitfalls of the CT and angiographic evaluation of metastatic disease.

Five patients with known primary malignancy demonstrated fatty infiltration of the liver on routine computed tomography (CT) examination. Within the diffuse fatty infiltration were focal areas of relatively increased beam attenuation in four cases. These areas of increased beam attenuation are nonspecific as to etiology. Their differential diagnosis is discussed. Since the true extent of the neoplastic process may be underestimated by conventional CT and celiac angiography, superselective angiography, computed angiotomography, or biopsy is required to accurately assess the etiology and the extent of the disease.

Adult↗
PubMed1982

Intraarterial management of giant-cell tumors of the spine in children.

Transcatheter arterial management of giant cell tumors of the spine was performed in two female patients aged 12 and 15 who had failed to respond to conventional therapy. Response was determined clinically by alleviation of pain and radiographically by regression and/or calcification of the tumor. Minor side effects included transient nausea, elevated body temperature, and pain.

Adolescent↗
PubMed1982

Experimental percutaneous renal embolization using BCG-saturated gelfoam.

Adult mongrel dogs (20-25 kg) were used to evaluate the administration of Bacillus Calmette-Guerin (BCG) in conjunction with total renal embolization for possible application in the management of metastatic renal cell carcinoma (RCC). Kidneys were surgically removed at 1, 2, and 3 weeks postembolization, examined grossly and microscopically, and then compared with kidneys embolized in the same manner without BCG. The procedure stimulated the reticuloendothelial system more than did renal embolization alone, and although a high dose (6 X 10(8) organisms) of BCG was administered, no complications were encountered. These results warrant a clinical trial of this technique in patients with advanced RCC.

Adenocarcinoma↗
PubMed1982

Angiographic appearance of recurrent malignant melanoma before and after intra-arterial chemotherapy.

Intra-arterial infusion of chemotherapeutic agents (CDDP alone or combined with DTIC) was used to treat recurrent melanoma in 22 patients. In 17 cases, sequential arteriograms were obtained before and after infusion to monitor the procedure. Pre-treatment angiograms usually demonstrated rounded nodules with a homogeneous, hypervascular stain. In 3 patients, additional deep-seated lesions which were not palpable clinically were detected by angiography. Arteriograms of those patients who responded to chemotherapy revealed partial or complete disappearance of tumor stain. A 46% response rate was observed. The authors feel that angiography is valuable in pre-treatment diagnosis and post-treatment evaluation of recurrent melanoma.

Angiography↗
PubMed1982

Injury to the intima of the hepatic artery. Results of follow-up in 11 cases.

Injury to the intima of the hepatic artery is an uncommon complication of selective arteriography. Eleven such cases were followed up for less than or equal to 12 months. The status of the vessels, the experience of the angiographer, and the materials used for catheterization all affected the frequency of injury, which was manifested by a spectrum of changes including an intimal flap, aneurysm, dissection, and occlusion. No patient had significant changes in liver function. Progression to complete arterial occlusion and regression with complete healing both occurred in this series.

Adult↗
PubMed1982

Angiographic classification of hepatic arterial collaterals.

Hepatic artery collaterals in 40 patients who had had hepatic artery occlusion following peripheral or central embolization, surgical ligation, intra-arterial chemotherapy, or intimal injury from catheterization were studied. The collaterals were classified as intrahepatic or extrahepatic collaterals. Intrahepatic arterial collaterals develop in the portal triads and subcapsular area between the lobes of the liver. Extrahepatic arterial collaterals develop in the ligaments that suspend the liver in the peritoneal cavity and through the structures that are closely attached to the liver. A simplified angiographic classification of hepatic arterial collaterals is presented.

Adenoma, Bile Duct↗
PubMed1982

Experimental canine hepatic artery embolization with polyvinyl alcohol foam particles.

Segmental and complete hepatic artery embolization with Ivalon (polyvinyl alcohol) particles (0.25 to 1 mm) was performed in 12 dogs to evaluate hepatic function alterations and histopathological changes. In dogs undergoing segmental embolization, liver function alterations were minimal and the liver was normal, both grossly and microscopically, at autopsy. In dogs undergoing complete hepatic embolization, only two had significant elevation of SGOT and alkaline phosphatase levels, which normalized in 2 and 4 weeks; one of these two dogs also had an elevated bilirubin level. A focal hepatic infarct was observed both grossly and microscopically in one dog and only microscopically in four dogs. Two dogs died of pancreatic abscess due to unintentional pancreatic embolization. The study suggested that segmental embolization with Ivalon particles was well tolerated by dogs, and complete hepatic embolization resulted in hepatic function changes and focal infarction comparable with Gelfoam embolization.

Alkaline Phosphatase↗
PubMed1982

Therapeutic Ivalon embolization of hepatic tumors.

Ivalon particles were used for 80 hepatic artery embolizations in 50 patients who had either primary or metastatic hepatic neoplasms. Ten patients died within 1-5 months and the remaining 40 patients were still alive. The post-hepatic embolization syndrome was identical to that following Gelfoam embolization. Follow-up hepatic angiography in 20 patients revealed tumor response to embolization in 17 patients. Ivalon particles were easier to use and caused more peripheral and persistent occlusion than Gelfoam. The results suggest that Ivalon particles were safe and feasible for hepatic artery embolization.

Adult↗
PubMed1982

Radiographic and angiographic changes in osteosarcoma after intraarterial chemotherapy.

Transcatheter arterial infusion has improved the preoperative control of osteosarcoma. The conventional radiographs and angiograms of osteosarcoma were evaluated in 53 patients before and after treatment. In the responders, two types of calcifications representing healing are observed: peripheral and central. The calcification is readily differentiated from that of tumor new bone. Angiography revealed a decrease in tumor vascularity and stain in responding tumors. Excellent angiographic and pathologic correlation of these changes is presented.

Angiography↗
PubMed1982

Bone metastases from renal carcinoma. The preoperative use of transcatheter arterial occlusion.

Surgical treatment of hypervascular bone lesions can result in excessive operative blood loss. We reviewed the cases of eight patients who were operated on for hypervascular bone metastases from renal carcinoma after preoperative transcatheter embolization. The embolization was successful in six of these patients and their operative blood loss averaged only 550 milliliters (range, 450 to 750 milliliters). The reasons for failure in two patients were failure to recognize and embolize all major vessels supplying the tumor in the first and the presence of too many small vessels arising directly from the superficial femoral artery to embolize safely in the second. When surgical treatment of hypervascular bone metastases is indicated, consideration should be given to preoperative arterial embolization.

Adenocarcinoma↗
PubMed1981

Segmental renal artery embolization in solitary renal carcinoma.

Segmental renal artery embolization was performed as an alternative method to treat solitary renal carcinoma in 2 patients who were poor surgical candidates. In the first patient, a recurrent renal carcinoma in a solitary kidney was selectively embolized. Tumor aggression was observed eighteen months later. Recanalization of the segmental artery and collateral from the capsular artery required a second embolization. In the second patient with a transitional cell carcinoma involving the lower half of the only functioning kidney, segmental renal artery embolization successfully controlled his persistent gross hematuria.

Adenocarcinoma↗
PubMed1981

Pitfalls of CT findings in post-therapy testicular carcinoma.

Computed tomography demonstrated fibrotic or necrotic lesions in the retroperitoneum and liver that were indistinguishable from viable tumor in three patients who had undergone therapy for testicular carcinoma. Therefore, residual masses after therapy may not signify viable disease.

Adult↗
PubMed1981

Therapeutically infarcted tumors: ct findings.

The CT findings in 14 patients who underwent hepatic or renal embolizations are presented. In 11 patients who had postinfarction CT studies, linear, branching air collections were noted within the embolized tumor. In two patients the amount of air increased on later CT studies. This configuration of air suggested an abscess, but in no case was an abscess encountered. This air was located distal to the high density embolization material in four cases. In four cases the infarcted organ appeared denser due to "trapped contrast." The seven embolized livers did not change in size on follow-up examinations, while three renal tumors demonstrated variable size changes after embolization.

Air↗
PubMed1981

Ivalon embolization in abdominal neoplasms.

Polyvinyl alcohol foam (Ivalon) particles were used in arterial embolization of abdominal neoplasms for tumor devascularization. The Ivalon particles are available in two sizes: small (0.25-0.59 mm) and large (0.60-1.0 mm). Twenty-five tumor embolizations in 22 patients (16 hepatic neoplasms, five renal carcinomas, one lumbar metastasis) were performed during a 4 month period. Occlusion of the embolized artery was documented by angiography in 24 procedures and by surgery in the remaining one. The postembolization syndrome was the same as that following Gelfoam embolization. Ivalon particles compared with Gelfoam cubes are advantageous in: (1) being easier to use; (2) reaching smaller arteries; and (3) causing more permanent occlusion.

Abdominal Neoplasms↗