Search PubMedSearch

Biomedical subjects

C S Burton

Publications and source records attributed to C S Burton.

15 recordsLinked to original sources

Treatment of lymphangioma circumscriptum with tunable dye laser.

We present the case of a patient with lymphangioma circumscriptum that was successfully treated with a flashlamp pulsed dye laser. Dermatologists are aware of the use of the pulsed dye laser for the treatment of port-wine stains and other vascular lesions. This case report illustrates the usefulness of the pulsed dye laser for the treatment of another common dermatologic condition.

Adult

Merkel cell tumor.

A case of a rapidly growing Merkel cell tumor occurring on the lower extremity in an 83-year-old woman is reported. A brief review of the clinical characteristics of this tumor as well as its immunohistochemical and ultrastructural features are presented.

Age Factors

Letterer-Siwe disease in an adult.

Letterer-Siwe disease, a proliferative disorder of Langerhans' cells, usually affects children during the first year of life. A 67-year-old woman is described here whose initial manifestation was a characteristic skin eruption. The clinical, pathologic, and ultrastructural features of Letterer-Siwe disease are reviewed and their role in diagnosis discussed.

Aged

Familial aggregation of melanoma, basal cell carcinoma, and gastric adenocarcinoma.

A family with four cases of melanoma, seven cases of basal cell carcinoma, and two cases of gastric adenocarcinoma, is described. The proband, who had three different primary tumors, died of gastric cancer, as did his father. Four of the proband's six siblings were affected with melanoma or basal cell cancer, as were two of his three children. Both daughters of one melanoma patient developed basal cell cancers. No spouses were affected, the cases were widely separated in time and place, and no unusual exposures were reported. HLA analysis of affected and unaffected first-degree relatives showed no association with antigens previously described in familial melanoma or segregation with a specific HLA haplotype. Although there was no association with HLA phenotype, these results suggest that melanoma, basal cell carcinoma, and gastric adenocarcinoma can be inherited in an autosomally dominant pattern similar to other familial tumor syndromes.

Adenocarcinoma

Jacob.

Explore the source record for details and available documents.

Adult

Primary lymphocutaneous Nocardia brasiliensis infection.

We report a rare case of primary lymphocutaneous Nocardia brasiliensis infection occurring in an elderly diabetic man maintained on long-term therapy with prednisone. The mode of inoculation was that of a puncture wound caused by a contaminated needle that occurred one month prior to the development of the clinically apparent infection. The course of this patient's infection was protracted and required two surgical procedures and several months of antibiotic therapy. A review of 15 previously reported cases is presented as well as a discussion of appropriate medical therapy.

Combined Modality Therapy

Necrotizing sialometaplasia: a sheep in wolf's clothing. Healing as a diagnostic test.

Necrotizing sialometaplasia is a benign self-limited intraoral lesion that is easily confused both clinically and histologically with squamous cell carcinoma. It presents as a painless ulceration, frequently on the hard palate, that histologically shows necrosis, inflammation, squamous metaplasia, and granulation tissue. It is thought to be due to infarction of minor salivary glands and heals spontaneously in six to 12 weeks. A brief period of observation for evidence of healing can be an important diagnostic clue in distinguishing this entity from cancer, thus saving the patient unnecessary surgery or radiation therapy.

Carcinoma, Squamous Cell

Premature sebaceous gland hyperplasia: successful treatment with isotretinoin.

Hyperplasia of sebaceous glands is a common cause of papulonodular facial lesions that occur in middle-aged and older patients. Recently, several cases of premature sebaceous gland hyperplasia have been reported. In these patients the lesions had persisted despite vigorous attempts at therapy. We present a case of premature sebaceous gland hyperplasia that was successfully treated with isotretinoin.

Adult

Pruritus ani.

Explore the source record for details and available documents.

Humans