[The arteriographical diagnosis of Wilms' tumour (author's transl)].
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Biomedical subjects
Publications and source records attributed to C Rossi.
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Three atypical patterns of cardiac failure and pulmonary edema, as frequently seen in chronic obstructive pulmonary diseases, are described; I. regional; II. miliary-like; III. Swiss-cheese like. Their importance in early diagnosis of pulmonary edema is discussed in the light of a review of a series of 98 patients whose pulmonary function was also investigated. Examples and statistical data are drown from this series.
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Asymptotic genotypic frequencies are evaluated as functions of selection parameters and initial conditions of a phenotypic diffusion process. On the basis of asymptotic relations between genotypic frequencies some analytic results about equilibrium are obtained.
In coronary artery disease the patients usually manifest both anxiety and depression disturbances. A controlled clinical study was conducted to test the efficacy of a new antidepressant agent, maprotiline, in the early stages of acute myocardial infarction. The sample consisted of 126 patients, sixty-three receiving orally 25 mg of maprotiline twice daily and the remainder 5 mg of diazepam twice daily. Treatment lasted on an average two weeks (ten days to eight weeks). The depressive and/or anxiety conditions were rated on the basis of a questionnaire administered before and after treatment. Depression improved markedly in patients receiving maprotiline, while the two drugs developed a comparable anxiolytic action. Tolerability was good. No clinical or ECG evidence of cardiotoxic signs was detected. The importance of a drug with these characteristics in the management of emotional disturbances in the early stages of coronary artery disease is emphasized.
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Total lipids, lipid classes, and per cent composition of fatty acids were investigated in plasma and stored subcutaneous fats of 19 subjects undergoing extracorporeal circulation (ECC). The tests were made before and 3, 20, 40, and 60 minutes after ECC was started. Hemodilution caused a general fall in total lipids and lipid classes. Evaluation of the lipid classes as percentages of the total lipids assumed to be 100 per cent allow the lipid variation due to hemodilution to be disregarded. A linear correlation between an increase in free fatty acids (FFA) and a decrease in triglycerides can thus be observed. This has been attributed to action of the lipase lipoproteic (LLP) activity stimulated by heparin, which is usually employed in ECC hemodilution. The hypothesis that FFA's are mobilized from stored subcutaneous fats was discounted.
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Two groups of patients were studied with serial correlated radiological functional analysis. Each group had a previous history of chronic obstructive pulmonary disease; however, on admission, only one group exhibited the clinical signs of this superimposed disease. The results of this research showed that chronic pulmonary disease is better defined by functional studies while cardiac failure (even in early stages) is always revealed by radiological examination.
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