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C Rosenblatt

Publications and source records attributed to C Rosenblatt.

At least 37 records · Page 2Linked to original sources

Orientation of lipid tubules by a magnetic field.

Lipid tubules, which are straight hollow cylinders consisting of lipid bilayers, are shown to orient in strong magnetic fields. Birefringence measurements were made of dilute samples of tubules of 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC23PC) in magnetic fields of up to 4 T. The tubules were found to orient with their long axes parallel to the field direction, with saturated orientation [P2 (cos theta] approximately greater than 0.95) found at approximately 2 T. From known distributions of lengths and the number of bilayers in the walls, a value delta chi = (-7 +/- 1) X 10(-9) erg cm-3 G-2 was calculated for the tubules, which compares well with some previously reported values for phosphatidylcholines. Magnetic alignment will permit more sophisticated structural studies of monomeric and polymeric tubules, and provide a method of orienting macromolecules in the tubule walls or interior.

Birefringence↗