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Biomedical subjects

C Rodrigues

Publications and source records attributed to C Rodrigues.

At least 73 records · Page 4Linked to original sources
PubMed1981

Placenta previa and previous cesarean section.

In a retrospective analysis over the six year period, January, 1973 to December, 1978, the incidence of placenta previa in cases with previous cesarean section (C.S.) was found to be 3.9 per cent as compared to an overall incidence of 1.9 per cent (p less than 0.01). The risk of placenta previa was greater in the pregnancy immediately following the cesarean section. The incidence of a morbidy adherent placenta was also significantly higher in these cases.

Cesarean Section↗
PubMed1972

The influence of game animals on the distribution and feeding habits of glossina pallidipes in the Lambwe Valley.

The role of game animals as important hosts of some species of tsetse, including Glossina pallidipes, has been studied in detail in the Lambwe Valley area of Kenya. A large population of G. pallidipes existed in association with a varied community of game animals in the study area, and the investigation was designed to determine which of the hosts available to G. pallidipes were actively selected and whether the preferred hosts influenced the distribution of the tsetse population. Bushbuck (Tragelaphus scriptus) was found to be the preferred host of G. pallidipes and there was a positive correlation between the distribution of these two species. Buffalo and roan antelope were also selected for food but, because of their behavioural characteristics, neither was continually available to the tsetse population and they had no influence on its distribution.

Animals↗
PubMed1972

A technique for the bioassay of insecticide deposits on leaf and bark samples in relation to tsetse control operations.

During tsetse control operations it may be necessary to determine the effective toxicity and persistence of insecticide residues on vegetation. A simple method for preparing samples of twig bark for bioassay and an exposure apparatus that has been found very satisfactory for exposing tsetse flies to residues on leaves and bark are described. The apparatus is easily manipulated and involves little handling of the test material.

Biological Assay↗
PubMedDate not supplied

Histopathological and radioautographical studies on the forestomach of F344 rats treated with butylated hydroxyanisole and related chemicals.

Butylated hydroxyanisole, when fed to male Fischer 344 rats for periods of 9 days or more, led to forestomach epithelial cell necrosis and regeneration. Both the induced proliferation and the histopathological changes were considerably more prevalent in the prefundic region of the forestomach than in the mid-region. Using [Me-3H]thymidine, a specific DNA precursor, and radioautography it was shown that the effect of the antioxidant was apparently threshold at 0.25% in the diet after both 9 days and 3 months of treatment and that the proliferation was dependent on the continuous presence of the antioxidant in the diet at 3 and 6 months. Some other phenols and acids were investigated after 9-27 days' feeding; most induced some degree of epithelial cell proliferation in the rat forestomach, although some had a greater effect on the mid-region than on the prefundic region. These observations are discussed in terms of the likely relevance of butylated hydroxyanisole-induced forestomach tumours to the possibility that the antioxidant may lead to cancer in humans exposed to lower levels in their diet.

Administration, Oral↗
PubMedDate not supplied

Reaction of rectal mucosa of celiac patients to direct contact with gluten.

It is assumed that the colonic mucosa of celiac patients is not sensitive to gluten. This assumption has been supported by the absence of clinical manifestations of colonic involvement in patients with active celiac disease which, by itself, does not confirm insensitivity to gluten. Eight children, aged from 11 to 25 months, with an initial diagnosis of celiac disease were studied: in five children a definite diagnosis has already been confirmed. Rectal gluten challenge was done by means of retention enemas. A volume of 100 ml of a 10% gluten suspension in water was introduced into the rectum three times per day for 8 days; each enema was retained at least 1 h. Rectosigmoidoscopies and rectal biopsies were done before and at the end of the challenge period. The endoscopic appearance of rectal mucosa was normal in all the children either before or after gluten challenge. The means of total mucosal thickness, intraepithelial lymphocyte counts, mitotic crypt cell activity, and cellular infiltration of lamina propria increased after challenge; the mean of goblet cell/epithelial cell ratio in the surface epithelium decreased. The differences between each pair of means (before and after challenge), however, were not significant except for total mucosal thickness (p less than 0.05), the meaning of which is unclear. This study did not definitely demonstrate that the rectal mucosa of celiacs is insensitive to gluten. For practical clinical purposes, however, it behaves as such. This makes the rectal mucosa a useless tool for the final diagnosis of celiac disease.

Administration, Rectal↗
PubMedDate not supplied

Performance improvement in pain management for home care and hospice programs.

This performance improvement project was undertaken to determine staff competency in pain management in several home care and hospice programs. The process used involved identifying and establishing the project, diagnosing the cause, remedying the cause, and holding the gains. Once the problem was identified and confirmed, the group worked to improve the competency of staff.

Clinical Competence↗