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Biomedical subjects

C Robinson

Publications and source records attributed to C Robinson.

At least 469 records · Page 26Linked to original sources

Recent changes in the emotional reactions of therapeutic aboriton applicants.

The emotional status of one hundred women applying for therapeutic abortions during 1967/68 was compared with that of 100 more recent applicants in 1975. The Minnesota Multiphasic Personality Inventory of the two groups reveals a significant reduction in psychopathology amongst the more recent applicants. This difference remains when group differences in age are controlled, and applies when married and single subgroups are considered separately. These results are interpreted as suggesting that the generally more liberal social atmosphere surrounding present-day abortions is reducing psychological stress among women undergoing this procedure.

Abortion, Therapeutic↗

Degradation of porstaglandin F2alpha in the human pulmonary circulation.

Degradation of prostaglandins (PGs) during passage through the human pulmonary circulation was investigated by measuring the transpulmonary plasma PGF2 alpha difference during continuous intravenous infusion of PGF2 alpha (5-10 mug/min). Seven patients with cardiological disorders and two patients with extensive pulmonary abnormalities were investigated during diagnostic cardiac catheterization. PGF2 alpha levels were measured by radioimmunoassay. The seven cardiac patients were found to have transpulmonary PGF2 alpha differences of 47-88%, indicating metabolism of the PG in the lungs. A patient with extensive bronchiectasis had an apparently normal transpulmonary PGF2alpha difference despite gross abnormalities in routine lung function tests. A patient with primary pulmonary arterial hypertension showed no metabolism of PGF2alpha in the pulmonary circulation. The results show that PG degradation is an aspect of normal lung function and suggest that it becomes imparied when extensive pulmonary vascular damage exists.

Adolescent↗

Variations in the composition of developing rat incisor enamel.

The developing enamel of rat incisors was dissected into a series of samples extending from the newly-formed partially-mineralised matrix to the mature.enamel. Chemical analysis showed that, on a dry weight basis, the tissue achieved the composition of mature enamel well before the completion of mineral uptake. The enamel at this stage was porous and relatively soft. As more mineral was acquired, its hardness increased. Throughout the developing region, the Ca:P ratio remained fairly constant, but the CO2:P and Mg:P ratios both decreased due, apparently, to dilution by an influx of relatively C02- and Mg-free mineral.

Amelogenesis↗