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Biomedical subjects

C Reyes

Publications and source records attributed to C Reyes.

48 records · Page 3Linked to original sources
PubMed1980

The outflow pathway in congenital glaucoma.

We obtained specimens from the angle of the eye during a trabeculotomy-trabeculectomy operation of a 5-month-old boy with congenital glaucoma. Light and electron miscroscopy of the anterior chamber angle showed the presence of mesodermal tissue covering the entire trabecular area. The trabecular meshwork showed thickening of trabecular beams, and an increased amount of collagen fibrils in the trabecular matrix. Internal trabecular spaces contained red blood cells; outer trabecular spaces were not apparent. The juxtacanalicular trabecular meshwork was thicker than in normal cases, because of an increased amount of collagen fibrils. The endothelium of Schlemm's canal was underlined by a thick and constant layer of amorphous material. These observations suggested that the site of increased resistance to aqueous humor outflow in congenital glaucoma could be found in abnormalities of the trabecular meshwork and the internal wall of Schlemm's canal.

Anterior Chamber↗
PubMed1977

Case report: miliary blastomycosis with cerebral involvement.

A patient was diagnosed as having labyrinthitis and an intracranial brain tumor. At the time a very fine nodularity to the bronchopulmonary markings was noted on the chest roentgenogram. Subsequent follow up examination revealed diffuse nodular densities throughout both lung fields having the appearance of a miliary distribution. Antituberculous therapy was begun empirically, but the patient expired within three weeks. At autopsy multiple granulomas were found in the cerebrum, cerebellum and meninges. By culture and histologic examination, these were determined to contain Blastomyces dermatitidis. The lungs contained numerous small granulomata almost to the exclusion of native pulmonary architecture. Lesions were also seen in spleen, lymph nodes and pancreas.

Blastomycosis↗
PubMedDate not supplied

Retrospective assessment of antibiotic and tourniquet use in an ambulatory surgery center.

In this study, 459 lower extremity surgeries were evaluated to assess and improve the quality of patient care at the Carnegie Surgery Center, Cleveland, Ohio. Two aspects of surgery were studied: the antibiotic usage and tourniquet application. The authors analyzed the rate of infection and the number of tourniquet complications that resulted from the surgeries. The infection rate was 0.65%, and there were no tourniquet complications. Using the information learned from the study and reviewing pertinent literature, recommendations were made to further enhance patient care.

Anti-Bacterial Agents↗
PubMedDate not supplied

Fine needle aspiration biopsy of intraoral and pharyngeal lesions.

Fine needle aspiration biopsy (FNAB) of superficial and deep-seated lesions has been used extensively with high sensitivity and specificity. However, reports of intraoral FNABs are sparse. We present a series of 44 intraoral FNABs performed between September 1988 and January 1992 at Loyola University Medical Center (36 cases) and Hines Veterans Administration Hospital (8 cases). The age of the patients ranged from 29 to 90 years (mean, 61), with 25 males and 19 females. Biopsy sites included buccal mucosal lesions (13 cases), pharynx/nasopharynx (11), tongue (10), tonsils (6), soft palate and epiglottis (2 each). Of the 44 cases, 32 (72.7%) had follow-up surgical biopsy, and 11 (25%) (all with benign diagnosis) were followed clinically. One aspiration was unsatisfactory. Cytologic diagnosis correlated with tissue biopsy in 25 cases (80.6% sensitivity). In six cases the cytologic material did not reveal a neoplasm found in the tissue sections (19.4% false negative). In one case the cytologic diagnosis of malignancy did not correlate with the surgical biopsy (3.1% false positive; specificity, 96.9%). The results of our study suggest that FNAB of intraoral lesions is less sensitive and specific than that of superficial masses. This may be explained by the small size and superficial location of the lesions as well as by the limited space for maneuvering the needle, with difficulty in fixing the lesion for adequate aspiration.

Adult↗
PubMedDate not supplied

Regular physical activity and reduced occurrence of microalbuminuria in type 2 diabetic patients.

In order to evaluate the influence of regular non-strenuous physical exercise on the appearance of microalbuminuria in Type 2 (non-insulin-dependent) diabetic patients, we have studied a cohort of 372 Type 2 diabetic patients (152 males and 220 females, mean age: 63.59 +/- 0.70 years, evolution time: 10.31 +/- 0.4 years, M +/- SEM). One hundred and ninety seven (52.9%) presented normo-albuminuria, 124 (33.3%) microalbuminuria and 51 (13.7%) proteinuria. These three groups were different with regard to evolution time, weight, BMI, waist-hip ratio, Hb1Ac value, prevalence of hypertension and physical activity level. 132 (35.4%) patients had a regular exercise-induced caloric expenditure under 500 kcal/wk whereas 122 (32.7%) were between 500 and 1.000 kcal/wk and 118 (31.7%) over 1.000 kcal/wk. Prevalence of normo-albuminuric patients was 40.1%, 52.4% and 67.7% respectively (p < 0.01). Prevalence of normo-albuminuric patients remained significatively higher in the patient with the greater physical activity level when adjusted to systolic blood pressure, diastolic blood pressure, evolution time and HbA1c value. Our results stress the fact that regular non-strenuous physical activity may have a protective effect on the appearance of microalbuminuria in Type 2 (non-insulin-dependent) diabetic patients. Whether the cardiovascular protective influence of exercise in these patients depends on such an effect remains unknown. On the basis of this cross-sectional evidence, a longitudinal study is now under way.

Aged↗