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Biomedical subjects

C Rey

Publications and source records attributed to C Rey.

At least 397 records · Page 22Linked to original sources
PubMed1977

Response of spleen lymphocytes shortly after thymectomy in adult mouse.

The blastogenesis response to the phytomitogens, PHA-P, Con A and PWM was used to assess the effect of adult thymectomy on the spleen lymphocytes of C57B1 mice. The mitogenic response to the phytomitogens was determined by 3H-thymidine uptake. The changes produced in theta-antigen bearing spleen lymphocytes were also evaluated making use of theta antibodies from AKR/S mice previously injected with splenic and thymic lymphocytes from CBA/J mice. The present results show that the response to mitogens PHA-P and Con A is reduced early after thymectomy while the response to PWM was only slightly reduced. There was not any correlation between the disminished response to mitogens and the changes observed in theta bearing spleen lymphocytes.

Age Factors↗
PubMed1977

[Contribution of echocardiography to the diagnosis of infradiaphragmatic total anomalous pulmonary venous return].

The authors report the case of a neonate with an abnormal pulmonary venous return which was totally infradiaphragmatic. Multiscan and monoscan echocardiography made the diagnosis, demonstrating an echo-free zone behind the left atrium extended backwards behind the mitral ring and the left ventricle. The child underwent successful surgery, and a follow-up echocardiogram showed that this abnormal space was lessened, responding with the collecting trunk.

Echocardiography↗
PubMed1977

[Cerebral abscess due to abnormal caval return].

A case of abnormal venous return is reported. It was discovered during investigation of a cerebral abscess. There was a persisting and unique left superior vena cava, draining in the left atrium. No other cardiac malformation was present. This abnormality is rare as only 2 other cases have been reported. It should be suspected in children presenting with cyanosis, clubbing of the fingers and left ventricular hypertrophy on electrocardiography.

Brain↗
PubMed1976

[The effects of Triton WR 1339 on the secretion of bile lipids in the rat].

Rats bearing a biliary fistula received i.v. a solution of Triton WR 1339. Bile and plasma lipid composition was studied every 2 hrs and compared to that of control rats injected with saline. Two hours after Triton injection a sharp decrease in the bile secretion of lecithins (-- 93%), cholesterol (-- 50%) and bile salts (-- 50%) was observed together with a fall in bile flow (-- 20%). Eight hours after Triton administration the biliary output of lecithins, cholesterol and bile salts was lowered to --73%, --50% and --34% respectively compared to control animals. At that time an accumulation of L.C.A.T. substrates (lecithins and cholesterol) was observed in the plasma of Triton group. These modifications of biliary lipids after inhibition of L.C.A.T. activity by Triton W 1339 could be the result of a decreased production of plasma lysolecithins and cholesterol esters suggesting that both lipids could be important precursors for the synthesis of bile constituents. Furthermore this support the view that the production by the liver of plasma and bile lipids follows two distinct pathways.

Animals↗
PubMed1975

[Disturbances of pulmonary ventilation in association with cardiac disease in infants (author's transl)].

Numerous causes exist for disturbances in pulmonary ventilation in the newborn and infant. Amongst the exobronchic causes, those of cardiovascular origin are not rare. The difficulty in radiological diagnosis varies in relation with the anatomo-radiological appearance of the lesions and their aetiology. Ventilation disturbances are not always obvious. Simple techniques (high penetration films, oblique views, films in inspiration and expiration) make possible the topographical localisation of the lesions and the detection of any obstructive factor. These films should also be adequate as far as the aetiological diagnosis is concerned: severe left-right shunt, pulmonary valve agenesis, fibro-elastosis, retrotracheal left pulmonary artery. Obviously, angiocardiography is often necessary to confirm and accurately determine the nature of the "cardiovascular" lesion responsible. Such disturbances of pulmonary ventilation may either reveal or complicate a cardiac or vascular disorder in the newborn or infant. They often present marked therapeutic problems.

Aorta↗
PubMed1974

The liver in boutonneuse fever.

Hepatic lesions were studied for the first time in 13 cases of boutonneuse fever (Mediterranean exanthematous fever). The glutamic-oxalacetic transaminases were raised in eight patients, the glutamic-pyruvic transaminases showed an increase in 10 patients, alkaline phosphatases in seven of the 10 patients investigated, and conjugate bilirubin showed moderate increases in three patients. Five patients were studied histologically; this study showed lesions of a granulomatous type, similar to those described in Q fever, in three patients, fatty degeneration with marked alcoholism in another patient, and a normal liver in the last patient. Two of the three patients with granulomatous lesions showed a moderate increase in alkaline phosphatases. After this report boutonneuse fever must be included among the infectious conditions that can produce granulomas within the liver.

Alanine Transaminase↗
PubMedDate not supplied

Effect of vasodilators on hepatic microcirculation: a study of the inhibition of norepinephrine-induced vasoconstriction in the isolated perfused rat liver.

We studied the effects of a series of 16 vasodilators on the intrahepatic vasoconstriction induced by norepinephrine in the isolated perfused rat liver. The vasodilators were nonselective alpha-adrenergic antagonists (phentolamine, ifenprofil, isoxsuprine and buflomedil), a nonselective beta-adrenergic antagonist (propranolol) and an agonist (isoproterenol), an alpha 2-adrenergic agonist (clonidine), calcium channel blockers (verapamil and diltiazem), nitrovasodilators (nitroglycerin, sodium nitroprusside), papaverine and other unclassified vasodilators, some of them with rheological properties (diazoxide, vincamine, cinepazide, naftidofuryl and pentoxifylline). The most potent drugs were ifenprofil, phentolamine, isoxsuprine, clonidine, sodium nitroprusside and buflomedil. Diazoxide, papaverine, pentoxifylline and trinitrine were less powerful. Verapamil, diltiazem, propranolol, isoproterenol, vincamine, cinepazide and naftidofuryl were ineffective. We conclude that different classes of pharmacological agents have significant vasodilatory properties on the hepatic microvasculature. This offers interesting perspectives in the treatment of cirrhosis and stressful states where high levels of circulating norepinephrine may contribute to the altered liver perfusion.

Animals↗