Search PubMed⌕ Search

Biomedical subjects

C Raitta

Publications and source records attributed to C Raitta.

At least 91 records · Page 5Linked to original sources
PubMed1976

Lens changes in car painters exposed to a mixture of organic solvents.

The relationship between exposure to organic solvents and the prevalence of lens changes was studied in a group of 92 car painters and a comparison group of 92 engineers from the Finnish State Railways. Both groups were examined ophthalmologically. Among the 92 car painters, with a mean age of 34.9 years (range of 21--64 years; S.D. 10.4 years), two had been operated on for a cataract and 46 had lens changes, mainly nuclear sclerosis, clefts, lamellar separation, or cortical and subcortical opacities not affecting visual acuity. In 69 age-matched pairs, for whom the factors inducing false-positive results had been excluded, 2 car painters had more lens changes than their age-matched pairs. Lens changes occurred with increased frequency after 10 years of exposure.

Adult↗
PubMed1976

Conventional pituitary irradiation in acromegaly. Effect on growth hormone and TSH secretion.

Thirty-one patients who had been treated for acromegaly for 1-21 years with conventional pituitary irradiation were re-examined. Immunoreactive growth hormone (GH) was measured in connection with an oral glucose load. Adrenal and gonadal functions were assessed on the basis of plasma cortisol and the urinary excretion of 17-ketogenic steroids, 17-ketosteroids and gonadotrophins. In evaluating the thyroid-pituitary axis the thyrotrophin-releasing hormone stimulation test (TRH) was used. Initially 30 patients had experienced definite benefit from the treatment but at the time of re-examination 10 still had clinically active disease and required another type of treatment. Normal GH levels (less than 5 ng/ml/1) were seen in only 12 patients. Skin thickness was normal in 15 out of 30. Thus the remission rate can be evaluated as being 67% as regards clinical activity, 50% with regard to skin thickness and 39% in terms of GH levels. Hypogonadism occurred in 12 patients (39%) and adrenal and thyroid failure in 5 patients each (16%). The response to TRH was within the normal range in 2 of the hypothyroid patients. In 22 euthyroid patients the mean increment in serum TSH in response to 200 mug of synthetic TRH was only 5.8 mU/1 which was significantly below the normal mean 12.5 mU/1. Furthermore, in 7 of these patients (32%) the response was absent or subnormal (less than 3.0 mU/1). This indicated that the pituitary is capable of secreting enough TSH for maintenance of an euthyroid state but that its capacity is limited. Conventional pituitary irradiation is not a very effective treatment in acromegaly but may still be recommended in selected cases.

Acromegaly↗
PubMed1975

Ocular pulse wave in workers exposed to carbon disulfide.

Oculosphygmography (OSG), combined with electrocardiography, was performed on 38 male workers exposed occupationally to carbon disulfide (CS2) and 40 unexposed male paper mill workers. A statistical analysis of the results showed that the ocular pulse wave of the exposed group showed a significantly lower pattern than that of the unexposed group. A comparison between workers currently exposed to CS2 and those no longer exposed indicated that the hemodynamic alterations caused by CS2 exposure lead to a permanent condition. It is concluded that CS2 exposure increases the rigidity of the vascular bed of the eye. The data indicate that primarily chronic, subclinical CS2 poisoning causes capillary damage. Oculosphygmography seems to be one objective examination useful in diagnosing the subtle syndrome of chronic CS2 poisoning.

Adult↗
PubMed1975

Mulibrey nanism: review of 23 cases of a new autosomal recessive syndrome.

Mulibrey (muscle, liver, brain, eye) nanism is probably an autosomal recessive condition characterized by progressive growth failure of prenatal onset, triangular face with hydrocephaloid skull, general thinness and muscular hypotonicity, peculiar voice, venous congestion caused by pericardial constriction, and pigment dispersion and yellowish dots in ocular fundi. Two thirds of the patients had cutaneous nevi flammei and one third cystic fibrous dysplasia of the tibia. Probably a substantial portion of the affected are lost by early abortion and others by infantile death. The physical capacity and life expectancy seem to vary depending on the degree of the cardiac affection.

Adolescent↗