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Biomedical subjects

C Radu

Publications and source records attributed to C Radu.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[The synthesis of aldoxime ester derivatives with biological activity].

Continuing our investigations for obtaining etheric derivatives from the oximes of some carbonylic compounds, five carboxymethylic ethers of some aldoximes were synthetized. Their structure was confirmed by chemical and spectral analyses. The antimicrobial activity of the obtained products towards 6 microorganisms species was determined.

Anti-Bacterial Agents↗
PubMedDate not supplied

[The direction and motivation for an evolution in methods of antiulcer surgery].

A 23-year retroactive analysis of a heterogeneous series of observations with unfavourable tardy results after antiulcer surgeries showed that the most failures requiring a second surgery appear after large resections with gastrojejunal or gastroduodenal anastomosis and after vagotomies associated with gastric drainage. The most favourable tardy results followed the vagotomy associated with limited gastric resection (hemigastrectomy). This kind of intervention prevents the appearance of the ulcerous relapses and lowers significantly the incidence of the other type of post-surgical iatrogenic complications. The optimal protection against the ulcerous relapse given by vagotomy associated with hemigastrectomy permits a tactical adaptation of the intervention to the lesional and physiopathological characteristics of each case.

Anastomosis, Surgical↗
PubMedDate not supplied

[Synthesis and physicochemical and biological characteristics of phthalazine derivatives].

Further studies in view of obtaining new stable phtalasiniuilides present the synthesis and physico-chemical and biological characterization of certain derivatives obtained through the action of p-phenyl-phenacyl and p-nitro-phenacyl bromides upon R-phtalasine. The structure of the new products was confirmed by physicochemical and spectral analyses. The preliminary biological tests showed a moderate antimicrobial activity of certain studies compounds.

Bacteria↗
PubMedDate not supplied

[Pancreatic fistulas].

Based on 17 observations the authors review the major etiopathogenic, evolutive, clinical and therapeutic aspects of pancreatic fistulae. In 14 cases the cure was achieved by medical treatment while surgery was resorted to in only three cases. The medical measures are discussed, as well as the indications for surgical treatment.

Adult↗
PubMedDate not supplied

[Complications of surgery of cancer of the colon].

In the paper a systematic analysis is carried out of postoperative complications of colon surgery, 118 patients had complications, out of a total of 400 interventions on the colon. The complications are studied in relation with the time of their occurence and the localization of the neoplastic process, as well as from the point of view of the influence exerted by age and the "background" of the patients. A review is also made of the therapeutic attitudes required by the various complications, of the results obtained and finally a detailed analysis is presented of the causes that led to death of operated patients.

Adult↗